Powder: -20°C for 3 years | In solvent: -80°C for 1 year
PNU-176798 is an agent with antimicrobial.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
25 mg | 6-8 weeks | $ 1,520.00 | |
50 mg | 6-8 weeks | $ 1,980.00 | |
100 mg | 6-8 weeks | $ 2,500.00 |
Description | PNU-176798 is an agent with antimicrobial. |
In vitro | PNU-176798 is an agent of antimicrobial, with a minimum inhibitory concentration (MIC) of 1.4 μM for E. coli.PNU-176798 blocks translation, 70S initiation with IC50s of 0.53, and 32 μM, respectively. PNU-176798 inhibits fMet-tRNA binding to the 70S ribosomes, with an IC50 of 32 μM. PNU-176798 inhibits peptidyl transferase (IC50, 40 μM), and the inhibition is more pronounced in the presence of elongation factor P (EF-P). PNU-176798 markedly inhibits the EF-G-mediated translocation of fMet-tRNA (IC50, 8 μM)[1]. |
Molecular Weight | 360.36 |
Formula | C16H13FN4O3S |
CAS No. | 428861-91-0 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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PNU-176798 428861-91-0 Microbiology/Virology Antibacterial PNU176798 PNU 176798 inhibitor inhibit