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TFLLR-NH2

Catalog No. T7573 CAS 197794-83-5

Synonyms: TFLLR-NH2(2TFA)

TFLLR-NH2(2TFA) is an agonist of PAR1 (EC50 :1.9 μM).

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TFLLR-NH2, CAS 197794-83-5

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Purity: 98%

Biological Description

Chemical Properties

Storage & Solubility Information

Description	TFLLR-NH2(2TFA) is an agonist of PAR1 (EC50 :1.9 μM).
Targets&IC50	PAR1:1.9 μM(EC50)

Synonyms	TFLLR-NH2(2TFA)
Molecular Weight	647.822
Formula	C31H53N9O6
CAS No.	197794-83-5

Storage

Powder: -20°C for 3 years

In solvent: -80°C for 2 years

Solubility Information

DMSO: 10 mM

( < 1 mg/ml refers to the product slightly soluble or insoluble )

References and Literature

1. de Garavilla L, et al. Agonists of proteinase-activated receptor 1 induce plasma extravasation by a neurogenic mechanism. Br J Pharmacol. 2001 Aug;133(7):975-87. 1. Kawabata A , Kuroda R , Kuroki N , et al. Characterization of the protease-activated receptor-1-mediated contraction and relaxation in the rat duodenal smooth muscle[J]. Life Sciences, 2000, 67(20):0-2530. 2. Jia Y , Zhang S , Miao L , et al. Activation of platelet protease-activated receptor-1 induces epithelial-mesenchymal transition and chemotaxis of colon cancer cell line SW620[J]. Oncology Reports, 2015.

Related Products

Related compounds with same targets

SLIGRL-NH2 TRAP-6 PAR-4 Agonist Peptide, amide acetate PAR-4 Agonist Peptide, amide TFLLR-NH2 Thrombin Receptor Activator for Peptide 5 (TRAP-5) Protease-Activated Receptor-4 AC-264613

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Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

TFLLR-NH2 197794-83-5 G蛋白偶联受体 Protease-activated Receptor Thrombin receptors TFLLR NH2 Protease Activated Receptor (PAR) Inhibitor TFLLR-NH2(2TFA) TFLLR-NH-2 TFLLRNH2 inhibit inhibitor

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