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TMP920

Catalog No. T17108 CAS 1421837-45-7

Purity 98.00% Datasheet

TMP920 inhibits RORγt binding to the SRC1 peptide (IC50: 0.03 μM). TMP920 is a highly potent and selective RORγt antagonist.

TMP920, CAS 1421837-45-7

Pack Size	Availability	Price/USD
5 mg	inquiry	190.00
10 mg	inquiry	322.00
50 mg	inquiry	952.00
100 mg	inquiry	1616.00
200 mg	inquiry	inquiry
500 mg	inquiry	inquiry
1 mL * 10 mM (in DMSO)	inquiry	208.00

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Purity 98.00%

Datasheet

Biological Description

Chemical Properties

Storage & Solubility Information

Description	TMP920 inhibits RORγt binding to the SRC1 peptide (IC50: 0.03 μM). TMP920 is a highly potent and selective RORγt antagonist.
Targets&IC50	RORγt :ic50 0.03 μM,

Molecular Weight	454.56
Formula	C29H30N2O3
CAS No.	1421837-45-7

Storage

-20℃ 3 years powder

-80℃ 2 years in solvent

Solubility Information

DMSO: 62.5 mg/mL (137.50 mM), Need ultrasonic

( < 1 mg/ml refers to the product slightly soluble or insoluble )

Related Products

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TAK-828F Xylan Vimirogant AZD-0284 RORγt Inverse agonist 8 A-9758 S18-000003 FM26

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

Note:

1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.

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What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?
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What volume of a given 10 mM stock solution is required to make 20ml of a 50 μM solution?
Using the equation C1V1 = C2V2, where C1=10 mM, C2=50 μM, V2=20 ml and V1 is the unknown:
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The answer of 100 microliter (0.1 ml) appears in the Volume (start) box

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Tech Support

Answers to questions you may have can be found in the Inhibitor Handling Instructions. Topics include how to prepare stock solutions, how to store Products, and issues that need special attention for cell-based assays and animal experiments.

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.