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Taspine

Catalog No. TN5100 CAS 602-07-3

Taspine shows antitumor activity by modulating the EGFR signaling pathway of ERK1/2 and Akt in vitro and in vivo, it can inhibit growth and induce Apoptosis of HUVEC in a dose-dependent manner, it has shown meaningful Angiogenesis activity. Taspine exhibits a dose-related cicatrizant effect and an ED50 of 0.375 mg/kg.

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Taspine, CAS 602-07-3

Pack Size	Availability	Price/USD	Quantity
5 mg	Inquiry	$ 540.00
1 mL * 10 mM (in DMSO)	Inquiry	$ 550.00

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Purity: 98%

Biological Description

Chemical Properties

Storage & Solubility Information

Description

Taspine shows antitumor activity by modulating the EGFR signaling pathway of Erk1/2 and Akt in vitro and in vivo, it can inhibit growth and induce apoptosis of HUVEC in a dose-dependent manner, it has shown meaningful angiogenesis activity. Taspine exhibits a dose-related cicatrizant effect and an ED50 of 0.375 mg/kg.

Molecular Weight	369.37
Formula	C20H19NO6
CAS No.	602-07-3

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 2 years

Solubility Information

( < 1 mg/ml refers to the product slightly soluble or insoluble )

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Taspine 602-07-3 Angiogenesis Apoptosis Cytoskeletal Signaling JAK/STAT signaling MAPK PI3K/Akt/mTOR signaling Tyrosine Kinase/Adaptors ERK EGFR BCL VEGFR Akt inhibitor inhibit

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