Powder: -20°C for 3 years
In solvent: -80°C for 2 years
Taspine shows antitumor activity by modulating the EGFR signaling pathway of Erk1/2 and Akt in vitro and in vivo, it can inhibit growth and induce apoptosis of HUVEC in a dose-dependent manner, it has shown meaningful angiogenesis activity. Taspine exhibits a dose-related cicatrizant effect and an ED50 of 0.375 mg/kg.
Description | Taspine shows antitumor activity by modulating the EGFR signaling pathway of Erk1/2 and Akt in vitro and in vivo, it can inhibit growth and induce apoptosis of HUVEC in a dose-dependent manner, it has shown meaningful angiogenesis activity. Taspine exhibits a dose-related cicatrizant effect and an ED50 of 0.375 mg/kg. |
Molecular Weight | 369.37 |
Formula | C20H19NO6 |
CAS No. | 602-07-3 |
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
( < 1 mg/ml refers to the product slightly soluble or insoluble )
You can also refer to dose conversion for different animals. More
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Taspine 602-07-3 JAK/STAT信号通路 MAPK信号通路 PI3K/Akt/mTOR信号通路 蛋白酪氨酸激酶 凋亡 细胞骨架 血管生成 MAPK BCL EGFR ERK Akt VEGFR Inhibitor inhibitor inhibit