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Topilutamide

Catalog No. T13184Cas No. 260980-89-0
Alias Fluridil, BP766

Topilutamide (Fluridil) is a topical nonsteroidal antiandrogen.

Topilutamide

Topilutamide

Purity: 98.54%
Catalog No. T13184Alias Fluridil, BP766Cas No. 260980-89-0
Topilutamide (Fluridil) is a topical nonsteroidal antiandrogen.
Pack SizePriceAvailabilityQuantity
1 mg$51In Stock
5 mg$122In Stock
10 mg$198In Stock
25 mg$427In Stock
50 mg$648In Stock
100 mg$923In Stock
1 mL x 10 mM (in DMSO)$133In Stock
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Purity:98.54%
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Product Introduction

Bioactivity
Description
Topilutamide (Fluridil) is a topical nonsteroidal antiandrogen.
In vivo
One of the commonly used approaches to treat metastatic prostate cancer is via first-generation nonsteroidal anti-androgens (NSAAs), namely Flutamide, Nilutamide, Bicalutamide and Topilutamide[1].
AliasFluridil, BP766
Chemical Properties
Molecular Weight403.23
FormulaC13H11F6N3O5
Cas No.260980-89-0
Storage & Solubility Information
Storagestore at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 125 mg/mL (310.00 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.4800 mL12.3999 mL24.7997 mL123.9987 mL
5 mM0.4960 mL2.4800 mL4.9599 mL24.7997 mL
10 mM0.2480 mL1.2400 mL2.4800 mL12.3999 mL
20 mM0.1240 mL0.6200 mL1.2400 mL6.1999 mL
50 mM0.0496 mL0.2480 mL0.4960 mL2.4800 mL
100 mM0.0248 mL0.1240 mL0.2480 mL1.2400 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
1 Enter information below:
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