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Vomicine

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Catalog No. TN1026Cas No. 125-15-5

Vomicine is a natural product from Strychnos nux-vomica, the S. nux-vomica extracts show antihyperglycemic activity in experimental animals.

Vomicine

Vomicine

🥰Excellent
Purity: 99.46%
Catalog No. TN1026Cas No. 125-15-5
Vomicine is a natural product from Strychnos nux-vomica, the S. nux-vomica extracts show antihyperglycemic activity in experimental animals.
Pack SizePriceAvailabilityQuantity
1 mg$49In Stock
5 mg$118In Stock
10 mg$173In Stock
25 mg$293In Stock
50 mg$427In Stock
100 mgInquiryIn Stock
1 mL x 10 mM (in DMSO)$137In Stock
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Purity:99.46%
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Product Introduction

Bioactivity
Description
Vomicine is a natural product from Strychnos nux-vomica, the S. nux-vomica extracts show antihyperglycemic activity in experimental animals.
In vitro
Reinvestigation of Strychnos icaja Baillon resulted in the isolation of Vomicine, isostrychnine and of three new sungucine derivatives, named isosungucine (8), 18-hydroxy-sungucine (9) and 18-hydroxy-isosungucine (10). They were identified by detailed spectroscopic methods. The complete 1H- and 13C-NMR study of sungucine was also realized. Some of these compounds were highly active against Plasmodium falciparum in vitro and more particularly against the chloroquine-resistant strain[1]
Chemical Properties
Molecular Weight380.44
FormulaC22H24N2O4
Cas No.125-15-5
Smiles[H][C@@]12N3c4c(cccc4O)[C@@]11CCN(C)CC4=CCO[C@@]([H])(CC3=O)[C@]2([H])[C@@]4([H])CC1=O
Relative Density.1.44g/cm3
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 50 mg/mL (131.43 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.6285 mL13.1427 mL26.2854 mL131.4268 mL
5 mM0.5257 mL2.6285 mL5.2571 mL26.2854 mL
10 mM0.2629 mL1.3143 mL2.6285 mL13.1427 mL
20 mM0.1314 mL0.6571 mL1.3143 mL6.5713 mL
50 mM0.0526 mL0.2629 mL0.5257 mL2.6285 mL
100 mM0.0263 mL0.1314 mL0.2629 mL1.3143 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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