Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Yoda1 is a Piezo1 ion channel agonist (EC50s = 17.1 and 26.6 μM for murine and human Piezo1-transfected HEK293T cells, respectively)
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 39.00 | |
2 mg | In stock | $ 55.00 | |
5 mg | In stock | $ 87.00 | |
10 mg | In stock | $ 117.00 | |
25 mg | In stock | $ 243.00 | |
50 mg | In stock | $ 470.00 | |
100 mg | In stock | $ 689.00 | |
500 mg | In stock | $ 1,460.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 95.00 |
Description | Yoda1 is a Piezo1 ion channel agonist (EC50s = 17.1 and 26.6 μM for murine and human Piezo1-transfected HEK293T cells, respectively) |
Targets&IC50 | Piezo1 (human, Piezo1-transfected HEK293T cells):26.6 μM, Piezo1 (Piezo1-transfected HEK293T cells):17.1 μM |
In vitro | Yoda1 that acts as an agonist for both human and mouse Piezo1.?Functional studies in cells revealed that Yoda1 affects the sensitivity and the inactivation kinetics of mechanically induced responses[1]. |
Molecular Weight | 355.27 |
Formula | C13H8Cl2N4S2 |
CAS No. | 448947-81-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 28 mg/mL (80 mM), Sonification is recommended
You can also refer to dose conversion for different animals. More
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Yoda 1 448947-81-7 Membrane transporter/Ion channel Piezo Channel KcsA Potassium Channel Akt Yoda-1 PKB Inhibitor A431 cells HCAECs inhibit Protein kinase B ERK Piezo1 Extracellular signal regulated kinases Endothelial cells ERK1/2 Yoda1 inhibitor