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A2B receptor antagonist 2

Catalog No. T37793 CAS 784-90-7

A2B receptor antagonist 2 is an antagonist of Adenosine Receptor A2B (Ki = 2.30 μM for rA1, 6.8 μM for rA2A, 3.44 μM for hA2B).

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A2B receptor antagonist 2, CAS 784-90-7

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Purity: 98%

Biological Description

Chemical Properties

Storage & Solubility Information

Description	A2B receptor antagonist 2 is an antagonist of adenosine receptor A2B (Ki = 2.30 μM for rA1, 6.8 μM for rA2A, 3.44 μM for hA2B).
Targets&IC50	rA2A:6.8 μM (Ki), rA1:2.30 μM (Ki), hA2B:3.44 μM (Ki)

Molecular Weight	229.28
Formula	C12H15N5
CAS No.	784-90-7

Storage

Powder: -20°C for 3 years

In solvent: -80°C for 2 years

Solubility Information

DMSO: 2 mg/mL (8.72 mM), ultrasonic and warming and heat to 60°C

Methanol: 5 mg/mL (21.81 mM), ultrasonic and warming and heat to 60°C

( < 1 mg/ml refers to the product slightly soluble or insoluble )

References and Literature

1. Thomas R Webb, et al. Quinazolines as adenosine receptor antagonists: SAR and selectivity for A2B receptors. Bioorg Med Chem. 2003 Jan 2;11(1):77-85.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

A2B receptor antagonist 2 784-90-7 GPCR/G Protein Neuroscience Adenosine Receptor A-2B receptor antagonist 2 inhibit P1 receptor Inhibitor receptor A2B inhibitor

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