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Abciximab
Abciximab
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Concentration:2.34 mg/mL
Purity:SDS-PAGE:95.2%;SEC-HPLC:95.9%
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Abciximab
Catalog No. T76844Cas No. 143653-53-6
Abciximab (C7E3) is a mouse/human chimeric monoclonal antibody that is a potent glycoprotein IIb/IIIa inhibitor. Abciximab has anti-platelet aggregation and leukocyte adhesion, acting by binding to glycoproteins IIb/IIIa, vitronectin and Mac-1 receptors.
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose. | Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $213 | In Stock | |
| 5 mg | $563 | In Stock | |
| 10 mg | $886 | In Stock | |
| 25 mg | $1,330 | In Stock | |
| 50 mg | $1,780 | In Stock | |
| 100 mg | $2,430 | In Stock |
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | Abciximab (C7E3) is a mouse/human chimeric monoclonal antibody that is a potent glycoprotein IIb/IIIa inhibitor. Abciximab has anti-platelet aggregation and leukocyte adhesion, acting by binding to glycoproteins IIb/IIIa, vitronectin and Mac-1 receptors. |
| In vitro | Inhibiting platelet aggregation induced by physiologic and pathologic agonists, abciximab (C7E3) achieves this effect by binding to the platelet αIIbβ3 integrin[2]. Abciximab appears to have similar affinity for the αIIbβ3 and αvβ3 integrins and redistributes between them[2]. |
| In vivo | Effectively preventing neointimal hyperplasia, abciximab (C7E3) is administered at a dose of 0.25 mg/kg/day via intravenous infusion for 28 days[2]. |
| Alias | C7E3 |
| Cas No. | 143653-53-6 |
| Storage | store at low temperature | store at -20°C | Shipping with blue ice. |
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