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Apostatin-1 (Apt-1) is a novel TRADD inhibitor that binds to a pocket on the N-terminal TRAF2 binding domain of TRADD.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $31 | In Stock | |
2 mg | $44 | In Stock | |
5 mg | $72 | In Stock | |
10 mg | $122 | In Stock | |
25 mg | $247 | In Stock | |
50 mg | $397 | In Stock | |
100 mg | $589 | In Stock | |
500 mg | $1,280 | In Stock | |
1 mL x 10 mM (in DMSO) | $79 | In Stock |
Description | Apostatin-1 (Apt-1) is a novel TRADD inhibitor that binds to a pocket on the N-terminal TRAF2 binding domain of TRADD. |
In vitro | Apostatin-1 inhibited bortezomib induced apoptosis and ripk1 dependent apoptosis (RDA) with the IC50 of ~1μM. |
Alias | Apt-1 |
Molecular Weight | 345.5 |
Formula | C19H27N3OS |
Cas No. | 2559703-06-7 |
Smiles | CN1CCN=C1SC(C(=O)NC1CCCCCC1)c1ccccc1 |
Relative Density. | 1.21 g/cm3 (Predicted) |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||||||||||||||||||||||||||||||||
Solubility Information | Ethanol: 9 mg/mL (26.06 mM), Sonication is recommended. DMSO: 50 mg/mL (144.72 mM), Sonication is recommended. | ||||||||||||||||||||||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||||||||||||||||||||||
Ethanol/DMSO
DMSO
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