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Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $257 | In Stock | |
5 mg | $995 | In Stock | |
10 mg | $1,493 | In Stock | |
25 mg | $2,687 | In Stock |
Description | BAM 22P acetate is a potent opioid agonist. |
In vitro | Plasma BAM 22P acetate levels s cholestatic rats are significantly higher than those in control rats. Adrenal steady-state levels of proenkephalin mRNA, as determined by Northern blot hybridization analyses, are also increased significantly in cholestatic rats. These increases in proenkephalin mRNA levels are not paralleled by changes in adrenal BAM 22P acetate peptide levels, which are similar in cholestatic rats and their respective controls. Adrenal gland levels of BAM 22P acetate are similar in BDR and sham-resected rats (BDR, 1.10±0.39 ng/g; sham, 0.93±0.16 ng/g; NS). BAM 22P acetate levels in ANIT-treated and oil-gavaged controls are also similar (ANIT, 2.88±0.29 ng/g; control, 2.75±0.30 ng/g; NS). However, adrenal BAM 22P acetate levels are lower in BDR and sham-resected rats than in ANIT-treated and oil-gavaged controls (P<0.01). Acute cholestasis in the rat is associated with enhanced synthesis and secretion of the proen-kephalin-derived opioid peptide BAM 22P acetate from the adrenal gland[1]. |
Molecular Weight | 2899.27 |
Formula | C132H188N38O33S2 |
Cas No. |
Storage | store at low temperature,keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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