Shopping Cart
- Remove All
- Your shopping cart is currently empty
Matrine (Vegard), an alkaloid isolated from the Sophora genus, acts as a kappa opioid receptor agonist.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
25 mg | $36 | In Stock | |
50 mg | $53 | In Stock | |
100 mg | $74 | In Stock | |
200 mg | $119 | In Stock | |
500 mg | $263 | In Stock | |
1 mL x 10 mM (in DMSO) | $45 | In Stock |
Description | Matrine (Vegard), an alkaloid isolated from the Sophora genus, acts as a kappa opioid receptor agonist. |
In vitro | In human non-small cell lung cancer A549 and hepatocellular carcinoma SMMC-7721 cells, Matrine inhibits cell growth. Particularly, in A549 cells, Matrine induces apoptosis by reducing the Bcl-2 / Bax protein ratio. |
In vivo | In mice, the median lethal dose (LD50) of Matrine administered via intraperitoneal injection is 157 mg/kg. |
Alias | α-Matrine, Vegard, Matrinium, Matridin-15-one, (+)-Matrine |
Molecular Weight | 248.36 |
Formula | C15H24N2O |
Cas No. | 519-02-8 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||||||||||||||||||||||||||||||||
Solubility Information | Ethanol: 49 mg/mL (197.29 mM) H2O: 11 mg/mL (44.29 mM), Heating is recommended. DMSO: 45 mg/mL (181.18 mM) | ||||||||||||||||||||||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||||||||||||||||||||||
H2O/DMSO/Ethanol
DMSO/Ethanol
|
Copyright © 2015-2024 TargetMol Chemicals Inc. All Rights Reserved.