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Matrine

Catalog No. T2870Cas No. 519-02-8
Alias α-Matrine, Vegard, Matrinium, Matridin-15-one, (+)-Matrine

Matrine (Vegard), an alkaloid isolated from the Sophora genus, acts as a kappa opioid receptor agonist.

Matrine

Matrine

Purity: 100%
Catalog No. T2870Alias α-Matrine, Vegard, Matrinium, Matridin-15-one, (+)-MatrineCas No. 519-02-8
Matrine (Vegard), an alkaloid isolated from the Sophora genus, acts as a kappa opioid receptor agonist.
Pack SizePriceAvailabilityQuantity
25 mg$36In Stock
50 mg$53In Stock
100 mg$74In Stock
200 mg$119In Stock
500 mg$263In Stock
1 mL x 10 mM (in DMSO)$45In Stock
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Purity:100%
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Product Introduction

Bioactivity
Description
Matrine (Vegard), an alkaloid isolated from the Sophora genus, acts as a kappa opioid receptor agonist.
In vitro
In human non-small cell lung cancer A549 and hepatocellular carcinoma SMMC-7721 cells, Matrine inhibits cell growth. Particularly, in A549 cells, Matrine induces apoptosis by reducing the Bcl-2 / Bax protein ratio.
In vivo
In mice, the median lethal dose (LD50) of Matrine administered via intraperitoneal injection is 157 mg/kg.
Aliasα-Matrine, Vegard, Matrinium, Matridin-15-one, (+)-Matrine
Chemical Properties
Molecular Weight248.36
FormulaC15H24N2O
Cas No.519-02-8
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
Ethanol: 49 mg/mL (197.29 mM)
H2O: 11 mg/mL (44.29 mM), Heating is recommended.
DMSO: 45 mg/mL (181.18 mM)
Solution Preparation Table
H2O/DMSO/Ethanol
1mg5mg10mg50mg
1 mM4.0264 mL20.1321 mL40.2641 mL201.3207 mL
5 mM0.8053 mL4.0264 mL8.0528 mL40.2641 mL
10 mM0.4026 mL2.0132 mL4.0264 mL20.1321 mL
20 mM0.2013 mL1.0066 mL2.0132 mL10.0660 mL
DMSO/Ethanol
1mg5mg10mg50mg
50 mM0.0805 mL0.4026 mL0.8053 mL4.0264 mL
100 mM0.0403 mL0.2013 mL0.4026 mL2.0132 mL

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Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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