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Bersanlimab
🥰Excellent
Catalog No. T76927Cas No. 1987854-08-9
Alias BI-505
Bersanlimab (BI-505) is a fully human monoclonal antibody targeting Intercellular Adhesion Molecule-1 (ICAM-1), demonstrating anticancer properties and applicable for studying relapsed/refractory multiple myeloma.
Bersanlimab
🥰Excellent
Catalog No. T76927Alias BI-505Cas No. 1987854-08-9
Bersanlimab (BI-505) is a fully human monoclonal antibody targeting Intercellular Adhesion Molecule-1 (ICAM-1), demonstrating anticancer properties and applicable for studying relapsed/refractory multiple myeloma.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $347 | In Stock | |
| 5 mg | $886 | In Stock | |
| 10 mg | $1,530 | In Stock |
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CitedSelect Batch
Concentration:6.37 mg/mL
Purity:> 95%
Contact us for more batch information
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | Bersanlimab (BI-505) is a fully human monoclonal antibody targeting Intercellular Adhesion Molecule-1 (ICAM-1), demonstrating anticancer properties and applicable for studying relapsed/refractory multiple myeloma. |
| In vitro | Bersanlimab(BI-505) induces dose-dependent expression of ICAM-1 and programmed cell death (PCD) in Ramos, Raji, and Daudi lymphoma cells, with a dosage range spanning from 1 ng/mL to 1000 μg/mL [1]. |
| In vivo | Bersanlimab (BI-505), administered at a dose of 20 mg/kg via intraperitoneal injection twice a week for a continuous period of 21 days, significantly reduces tumor growth and prolongs the survival of animals [1]. |
| Alias | BI-505 |
| Molecular Weight | 144.22 kDa |
| Cas No. | 1987854-08-9 |
Storage & Solubility Information
| Storage | store at low temperature | store at -80°C | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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