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Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 mg | Inquiry | Backorder | |
500 mg | Inquiry | Backorder |
Description | Boc-gly-PEG3-endo-BCN is a PEG-based PROTAC linker and a cleavable 2-unit PEG ADC linker, used in the synthesis of PROTACs [1] and antibody-drug conjugates (ADCs) [2], respectively. |
In vitro | PROTACs consist of two ligands linked by a connector: one targets an E3 ubiquitin ligase, and the other targets a specific protein, utilizing the intracellular ubiquitin-proteasome system for selective degradation of target proteins[1]. ADCs are composed of an antibody conjugated to an ADC cytotoxin via an ADC linker[2]. |
Molecular Weight | 553.69 |
Formula | C28H47N3O8 |
Cas No. | 2110444-63-6 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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