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Boc-NH-C6-Br

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Catalog No. T17654Cas No. 142356-33-0

Boc-NH-C6-Br is a cleavable linker used in antibody-drug conjugates (ADC).

Boc-NH-C6-Br

Boc-NH-C6-Br

🥰Excellent
Purity: 95.09%
Catalog No. T17654Cas No. 142356-33-0
Boc-NH-C6-Br is a cleavable linker used in antibody-drug conjugates (ADC).
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200 mg$29In Stock
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Purity:95.09%
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Product Introduction

Bioactivity
Description
Boc-NH-C6-Br is a cleavable linker used in antibody-drug conjugates (ADC).
Chemical Properties
Molecular Weight280.2
FormulaC11H22BrNO2
Cas No.142356-33-0
SmilesC(NCCCCCCBr)(OC(C)(C)C)=O
Relative Density.1.192 g/cm3 at 20℃ (lit.)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 40 mg/mL (142.76 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.5689 mL17.8444 mL35.6888 mL178.4440 mL
5 mM0.7138 mL3.5689 mL7.1378 mL35.6888 mL
10 mM0.3569 mL1.7844 mL3.5689 mL17.8444 mL
20 mM0.1784 mL0.8922 mL1.7844 mL8.9222 mL
50 mM0.0714 mL0.3569 mL0.7138 mL3.5689 mL
100 mM0.0357 mL0.1784 mL0.3569 mL1.7844 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
1 Enter information below:
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2 Enter the in vivo formulation:
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Dose Conversion

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