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Boc-NH-PEG8-CH2CH2COOH is a PEG-based PROTAC linker utilized in PROTAC synthesis.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
50 mg | $29 | In Stock |
Description | Boc-NH-PEG8-CH2CH2COOH is a PEG-based PROTAC linker utilized in PROTAC synthesis. |
In vitro | PROTACs consist of two ligands joined by a linker: one binds to an E3 ubiquitin ligase, and the other to the target protein. This mechanism leverages the intracellular ubiquitin-proteasome system to selectively degrade target proteins [1]. |
Molecular Weight | 541.63 |
Formula | C24H47NO12 |
Cas No. | 1334169-93-5 |
Smiles | O(C(NCCOCCOCCOCCOCCOCCOCCOCCOCCC(O)=O)=O)C(C)(C)C |
Relative Density. | 1.122 g/cm3 (Predicted) |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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