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Boc-Val-Cit-PAB-PNP

🥰Excellent
Catalog No. T17692Cas No. 870487-10-8

Boc-Val-Cit-PAB-PNP is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

Boc-Val-Cit-PAB-PNP

Boc-Val-Cit-PAB-PNP

🥰Excellent
Purity: 97.9%
Catalog No. T17692Cas No. 870487-10-8
Boc-Val-Cit-PAB-PNP is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
Pack SizePriceAvailabilityQuantity
5 mg$31In Stock
10 mg$51In Stock
25 mg$79In Stock
50 mg$108In Stock
100 mg$158In Stock
500 mg$392In Stock
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Purity:97.9%
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Product Introduction

Bioactivity
Description
Boc-Val-Cit-PAB-PNP is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
In vitro
ADCs consist of an antibody attached to an ADC cytotoxin through an ADC linker.
Chemical Properties
Molecular Weight644.67
FormulaC30H40N6O10
Cas No.870487-10-8
SmilesCC(C)[C@H](NC(=O)OC(C)(C)C)C(=O)N[C@@H](CCCNC(N)=O)C(=O)Nc1ccc(COC(=O)Oc2ccc(cc2)[N+]([O-])=O)cc1
Relative Density.1.291 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 10 mM
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.5512 mL7.7559 mL15.5118 mL77.5591 mL
5 mM0.3102 mL1.5512 mL3.1024 mL15.5118 mL
10 mM0.1551 mL0.7756 mL1.5512 mL7.7559 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
1 Enter information below:
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2 Enter the in vivo formulation:
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