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Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $199 | In Stock |
Description | Butyrolactone 3 (MB-3) is a histone acetyltransferase Gcn5 inhibitor with a weak affinity for CBP.Butyrolactone 3 has antimicrobial activity and has been used in cancer, metabolic and neurological disorders. |
In vitro | Butyrolactone 3 (50, 100, 200 μM; 16 h; RCH-ACV cells) can reduce Gcn5 acetylation and induces E2A-PBX1 degradation. Butyrolactone 3 decreased the protein levels of E2A-PBX1 and E2A in a dose-dependent manner, and reduced Wnt16 and GCN5 protein levels.[3] |
Alias | MB-3, MB3, MB 3 |
Molecular Weight | 184.19 |
Formula | C9H12O4 |
Cas No. | 778649-18-6 |
Storage | store at low temperature Powder: -20°C for 3 years | In solvent: -80°C for 1 year | |||||||||||||||||||||||||||||||||||
Solubility Information | DMSO: 80 mg/mL (434.33 mM) | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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