Shopping Cart

Remove All

Your shopping cart is currently empty

BV02

Select Batch

Purity:99.79%

Resource Download

COA HPLC HNMR

BV02

Catalog No. T60081Cas No. 292870-53-2

BV02 is an inhibitor of 14-3-3 protein-protein interactions and can be used in studies about the treatment of chronic myeloid leukemia. BV02 disrupts hematopoietic cells expressing the IM-resistant T315I mutation and the IM-sensitive wild-type Bcr-Abl.

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Pack Size	Price	Availability
1 mg	$36	In Stock
2 mg	$52	In Stock
5 mg	$84	In Stock
10 mg	$128	In Stock
25 mg	$289	In Stock
50 mg	$455	In Stock
100 mg	$672	In Stock
500 mg	$1,430	In Stock
1 mL x 10 mM (in DMSO)	$94	In Stock

Bulk & Custom

Add to Cart

Questions

Related Compound Libraries of "BV02"

Product Introduction

Bioactivity

Description	BV02 is an inhibitor of 14-3-3 protein-protein interactions and can be used in studies about the treatment of chronic myeloid leukemia. BV02 disrupts hematopoietic cells expressing the IM-resistant T315I mutation and the IM-sensitive wild-type Bcr-Abl.
Alias	2-(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)-1,3-dioxoisoindoline-5-carboxylic acid

Chemical Properties

Molecular Weight	377.35
Formula	C20H15N3O5
Cas No.	292870-53-2

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 10 mg/mL (26.5 mM)

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.6501 mL	13.2503 mL	26.5006 mL	132.5030 mL
5 mM	0.5300 mL	2.6501 mL	5.3001 mL	26.5006 mL
10 mM	0.2650 mL	1.3250 mL	2.6501 mL	13.2503 mL
20 mM	0.1325 mL	0.6625 mL	1.3250 mL	6.6251 mL

Calculator

Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

Dose Conversion

You can also refer to dose conversion for different animals. More

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc