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CaV1.3 antagonist-1
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Catalog No. T61026Cas No. 1391385-57-1
CaV1.3 antagonist-1 is a selective CaV1.3L-type calcium channel antagonist useful for researching neurological disorders and cardiovascular diseases.
CaV1.3 antagonist-1
😃Good
Catalog No. T61026Cas No. 1391385-57-1
CaV1.3 antagonist-1 is a selective CaV1.3L-type calcium channel antagonist useful for researching neurological disorders and cardiovascular diseases.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 25 mg | $977 | 6-8 weeks | |
| 50 mg | $1,270 | 6-8 weeks | |
| 100 mg | $1,990 | 6-8 weeks |
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Product Introduction
Bioactivity
Chemical Properties
| Description | CaV1.3 antagonist-1 is a selective CaV1.3L-type calcium channel antagonist useful for researching neurological disorders and cardiovascular diseases. |
| Targets&IC50 | Cav 1.3:1.7 μM |
| In vitro | CaV1.3 antagonist-1 is a CAV1.3L calcium channel antagonist with an IC50 of 1.7 μM. CaV1.3 antagonist-1 (5μM) inhibited the CaV1.3 and CaV1.2 channel currents in HEK293 cells by 31.2% and 4.4%, respectively. [1] |
| Molecular Weight | 334.8 |
| Formula | C17H19ClN2O3 |
| Cas No. | 1391385-57-1 |
| Smiles | O=C1N(C(=O)CC(=O)N1C2CCCC2)CCC=3C=CC=C(Cl)C3 |
Storage & Solubility Information
| Storage | keep away from direct sunlight,store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 80 mg/mL (238.95 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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