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CDDO-2P-Im

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Purity:97.07%

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COA HNMR HPLC

CDDO-2P-Im

Catalog No. T13602Cas No. 1883650-96-1

CDDO-2P-Im shows chemopreventive effect and reduces the size and severity of the lung tumors in the mouse lung cancer model.

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Pack Size	Price	Availability
1 mg	$108	In Stock
5 mg	$228	In Stock
10 mg	$372	In Stock
25 mg	$615	In Stock
50 mg	$869	In Stock
100 mg	$1,170	In Stock
1 mL x 10 mM (in DMSO)	$313	In Stock

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Product Introduction

Bioactivity

Description	CDDO-2P-Im shows chemopreventive effect and reduces the size and severity of the lung tumors in the mouse lung cancer model.
In vitro	In RAW264.7 cells, CDDO-2P-Im suppresses NO production (IC50: 5.8 nM). CDDO-2P-Im (100 nM) induces differentiation of U937 cells[1].
In vivo	CDDO-2P-Im significantly elevates heme oxygenase-1 and quinone reductase mRNA and protein levels. In A/J mice, CDDO-2P-Im (50-200 mg/kg) decreases the number, size, and severity of tumors[1].
Alias	CDDO-2-P-Im

Chemical Properties

Molecular Weight	618.81
Formula	C39H46N4O3
Cas No.	1883650-96-1

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 112.5 mg/mL (181.8 mM)

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.6160 mL	8.0800 mL	16.1600 mL	80.8002 mL
5 mM	0.3232 mL	1.6160 mL	3.2320 mL	16.1600 mL
10 mM	0.1616 mL	0.8080 mL	1.6160 mL	8.0800 mL
20 mM	0.0808 mL	0.4040 mL	0.8080 mL	4.0400 mL
50 mM	0.0323 mL	0.1616 mL	0.3232 mL	1.6160 mL
100 mM	0.0162 mL	0.0808 mL	0.1616 mL	0.8080 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

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A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

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