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Description | CDK5-IN-3 (compound 11) is a highly potent and selective inhibitor of CDK5, demonstrating significant inhibition with IC50 values of 0.6 nM and 18 nM for CDK5/p25 and CDK2/CycA, respectively. This compound holds promise for further investigation in the context of autosomal dominant polycystic kidney disease (ADPKD) research [1]. |
Molecular Weight | 362.47 |
Formula | C22H26N4O |
Cas No. | 2639542-32-6 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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