Shopping Cart
- Remove All
- Your shopping cart is currently empty
Ceramides Mixture, an endogenous ceramide, consists of hydroxy and non-hydroxy fatty acid-containing ceramides. It is involved in the regulation of cell cycle arrest, growth inhibition, and modulation of telomerase activity.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $32 | In Stock | |
2 mg | $45 | In Stock | |
5 mg | $74 | In Stock | |
10 mg | $108 | In Stock | |
25 mg | $178 | In Stock | |
50 mg | $272 | In Stock | |
100 mg | $397 | In Stock | |
500 mg | $936 | In Stock |
Description | Ceramides Mixture, an endogenous ceramide, consists of hydroxy and non-hydroxy fatty acid-containing ceramides. It is involved in the regulation of cell cycle arrest, growth inhibition, and modulation of telomerase activity. |
In vitro | Endogenous Ceramides inhibits mRNA synthesis of telomerase reverse transcriptase and telomerase activity via inactivation of the c-Myc transcription factor in the A549 human lung adenocarcinoma cell line. The sustained generation of long-chain endogenous ceramide requires the biochemical recycling of the sphingosine backbone of C6-ceramide, which involves deacylation and reacylation of ceramide for the generation of endogenous long-chain ceramide, most likely by CoA-dependent ceramide synthase, which is inhibited by fumonisin B1. In A549 cells the generation of long-chain endogenous ceramide mediates the effects of exogenous C6-ceramide on growth inhibition, cell cycle arrest, and the modulation of telomerase activity [1]. |
Cas No. | 100403-19-8 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
Solubility Information | Methanol: < 1 mg/mL (insoluble or slightly soluble) Ethanol: 1 mg/ml, Sonication and heating for 30 minutes are recommended. H2O: < 1 mg/mL (insoluble or slightly soluble) DMSO: < 1 mg/mL (insoluble or slightly soluble) Chloroform: 7.69 mg/ml |
Copyright © 2015-2024 TargetMol Chemicals Inc. All Rights Reserved.