Shopping Cart
- Remove All
Your shopping cart is currently empty
L-778123 hydrochloride
🥰Excellent
Catalog No. T3182Cas No. 253863-00-2
Alias L 778123
The L-778123 hydrochloride is an inhibitor of FPTase (IC50: 2 nM) and GGPTase-I (IC50: 98 nM) in enzyme inhibition determination.
L-778123 hydrochloride
🥰Excellent
Purity: 98.51%
Catalog No. T3182Alias L 778123Cas No. 253863-00-2
The L-778123 hydrochloride is an inhibitor of FPTase (IC50: 2 nM) and GGPTase-I (IC50: 98 nM) in enzyme inhibition determination.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 2 mg | $38 | In Stock | |
| 5 mg | $61 | In Stock | |
| 10 mg | $89 | In Stock | |
| 25 mg | $159 | In Stock | |
| 50 mg | $262 | In Stock | |
| 100 mg | $442 | In Stock | |
| 1 mL x 10 mM (in DMSO) | $63 | In Stock |
Bulk & Custom
Add to Cart
Questions
View MoreInhibitors Related to "L-778123 hydrochloride"
Entacapone
OR-611
T2216130929-57-6
Entacapone (OR-611) is a selective and reversible inhibitor of catechol-O-methyltransferase (COMT).
- $30
Size
QTY
Risedronic Acid
Risedronate
T0379105462-24-6
Risedronic Acid (Risedronate), a pyridinyl biphosphonate, can inhibit osteoclast-mediated bone resorption.
- $35
Size
QTY
Serotonin hydrochloride
Cited
Serotonin HCl, 5-Hydroxytryptamine hydrochloride, 5-HT hydrochloride, 5-HT HCl
T2209153-98-0
Serotonin hydrochloride (Serotonin HCl) is an endogenous 5-HT receptor agonist, a monoamine neurotransmitter in the CNS, and a catechol O-methyltransferase (COMT) inhibitor(Ki=44 μM).
- $30
Size
QTY
CitedFlopropione Cited
Phloropropiophenone
T05252295-58-1
Flopropione (Phloropropiophenone), a spasmolytic or antispasmodic agent, is used as a 5-HT1A receptor antagonist.
- $30
Size
QTY
CitedAlendronate sodium trihydrate
G-704650 Adronat
T6373121268-17-5
Alendronate sodium hydrate (MK 217) is a nitrogen-containing bisphosphonate, which is an effective inhibitor of bone resorption. It is utilized for the treatment and prevention of osteoporosis.
- $40
Size
QTY
Rosmarinic acid Cited
Rosemary acid, Labiatenic acid
T276520283-92-5
Rosmarinic acid (Labiatenic acid) is widely found in plants and has antioxidant, anti-inflammatory, and antibacterial activities. It inhibits MAO-A, MAO-B, and COMT with IC50 of 50.1, 184.6, and 26.7 μM respectively.
- Inquiry Price
Size
QTY
CitedCeramides Mixture
T10760100403-19-8
Ceramides Mixture, an endogenous ceramide, consists of hydroxy and non-hydroxy fatty acid-containing ceramides. It is involved in the regulation of cell cycle arrest, growth inhibition, and modulation of telomerase activity.
- $32
Size
QTY
Costunolide
NSC 106404, Costus lactone, (+)-Costunolide
T2902553-21-9
Costunolide (Costus lactone) has anti-inflammatory and anti-oxidant properties and mediates apoptosis.
- $55
Size
QTY
Zidovudine Cited
ZDV, NSC 602670, AZT, Azidothymidine
T141630516-87-1
Zidovudine (ZDV) is a synthetic dideoxynucleoside. After intracellular phosphorylation to its active metabolite, zidovudine inhibits DNA polymerase, resulting in the inhibition of DNA replication and cell death. This agent also decreases levels of available pyrimidines.
- $44
Size
QTY
CitedOU749
T22128519170-13-9
OU749 is a γ-glutamyl transferase (GGT) inhibitor with an intrinsic Ki of 17.6 μM.
- $42
Size
QTY
Ibandronate sodium
Ibandronate sodium salt, Boniva, Bondronat
T1599L138844-81-2
Ibandronate sodium (Boniva) is a synthetic nitrogen-containing bisphosphonate, used for the treatment of osteoporosis.
- $76
Size
QTY
Cyclogalegenin
Cyclogalegigenin, Cyclogalagenin, Cycloastragenol, Astramembrangenin
T333384605-18-5
Cyclogalegenin (Astramembrangenin) is able to elongate telomeres, resulting in increased lifespan of the animals.
- $39
Size
QTY
Select Batch
Purity:98.51%
Contact us for more batch information
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | The L-778123 hydrochloride is an inhibitor of FPTase (IC50: 2 nM) and GGPTase-I (IC50: 98 nM) in enzyme inhibition determination. |
| Targets&IC50 | GGTase I:98 nM, FPTase:2 nM |
| Alias | L 778123 |
| Molecular Weight | 442.34 |
| Formula | C22H21Cl2N5O |
| Cas No. | 253863-00-2 |
| Smiles | Cl.Clc1cccc(c1)N1CCN(Cc2cncn2Cc2ccc(cc2)C#N)CC1=O |
| Relative Density. | no data available |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 50 mg/mL (113.04 mM)  | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
| ||||||||||||||||||||||||||||||||||||
Calculator
In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
Dose Conversion
You can also refer to dose conversion for different animals. More Dose Conversion
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Preview
Related Tags: buy L-778123 hydrochloride | purchase L-778123 hydrochloride | L-778123 hydrochloride cost | order L-778123 hydrochloride | L-778123 hydrochloride chemical structure | L-778123 hydrochloride formula | L-778123 hydrochloride molecular weight
- TOP
Feedback
Hello! How can I help you today? 
Copyright © 2015-2024 TargetMol Chemicals Inc. All Rights Reserved.