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Adefovir is an acyclic nucleoside phosphonate that acts as a reverse transcriptase inhibitor used for treatment of hepatitis B and herpes simplex virus infection.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
25 mg | $41 | In Stock | |
50 mg | $66 | In Stock | |
100 mg | $97 | In Stock | |
200 mg | $145 | In Stock |
Description | Adefovir is an acyclic nucleoside phosphonate that acts as a reverse transcriptase inhibitor used for treatment of hepatitis B and herpes simplex virus infection. |
In vitro | adefovir is a potent inhibitor of DHBV replication that inhibits CCC DNA amplification but does not effectively prevent the formation of CCC DNA from incoming viral genomes[1]. |
Cell Research | The effect of adefovir on viral CCC DNA synthesis was examined with primary cultures of DHBV-infected fetal hepatocytes.?Adefovir was administered for six consecutive days starting one day before or four days after DHBV inoculation.?Dose-dependent inhibition of both virion release in culture supernatants and synthesis of intracellular viral DNA was observed[1]. |
Molecular Weight | 273.19 |
Formula | C8H12N5O4P |
Cas No. | 106941-25-7 |
Smiles | CC(C)(C)C(=O)OCOP(=O)(COCCN1C=NC2=C1N=CN=C2N)OCOC(=O)C(C)(C)C |
Relative Density. | 1.88 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||
Solubility Information | H2O: 2.5 mM DMSO: Insoluble | ||||||||||
Solution Preparation Table | |||||||||||
H2O
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