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Chloramphenicol succinate
🥰Excellent
Catalog No. T25240Cas No. 3544-94-3
Alias Paraxin succinate, Kemicetine succinate, CPSA
Chloramphenicol succinate is a water-soluble prodrug of Chloramphenicol, a bacteriostatic antibiotic that binds to bacterial ribosomes to block their translation. CPSA is a competitive substrate and inhibitor of succinate dehydrogenase (SDH). In vitro, Kemicetine succinate can be oxidized by succinate dehydrogenase to release chloramphenicol.
Chloramphenicol succinate
🥰Excellent
Catalog No. T25240Alias Paraxin succinate, Kemicetine succinate, CPSACas No. 3544-94-3
Chloramphenicol succinate is a water-soluble prodrug of Chloramphenicol, a bacteriostatic antibiotic that binds to bacterial ribosomes to block their translation. CPSA is a competitive substrate and inhibitor of succinate dehydrogenase (SDH). In vitro, Kemicetine succinate can be oxidized by succinate dehydrogenase to release chloramphenicol.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $98 | In Stock | |
| 5 mg | $243 | In Stock | |
| 10 mg | $477 | In Stock | |
| 25 mg | $1,080 | In Stock | |
| 50 mg | $1,450 | In Stock | |
| 100 mg | $1,960 | In Stock | |
| 200 mg | $2,630 | In Stock |
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Product Introduction
Bioactivity
Chemical Properties
| Description | Chloramphenicol succinate is a water-soluble prodrug of Chloramphenicol, a bacteriostatic antibiotic that binds to bacterial ribosomes to block their translation. CPSA is a competitive substrate and inhibitor of succinate dehydrogenase (SDH). In vitro, Kemicetine succinate can be oxidized by succinate dehydrogenase to release chloramphenicol. |
| In vitro | Methods: RAW264.7 cells were treated with N,N-Dimethylsphingosine (0-5μM, 24 hours), and cell viability was determined by MTT assay. Results: N,N-Dimethylsphingosine can inhibit the growth of RAW264.7 cells with an IC50 value of 2.3μM. [1] |
| Alias | Paraxin succinate, Kemicetine succinate, CPSA |
| Molecular Weight | 423.2 |
| Formula | C15H16Cl2N2O8 |
| Cas No. | 3544-94-3 |
| Smiles | O[C@@H]([C@@H](COC(=O)CCC(O)=O)NC(=O)C(Cl)Cl)c1ccc(cc1)[N+]([O-])=O |
| Relative Density. | 1.536g/cm3 |
Storage & Solubility Information
| Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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