Shopping Cart
- Remove All
![TargetMol](https://newstatic.targetmol.com/error/oops.webp)
Your shopping cart is currently empty
Pack Size | Price | Availability | Quantity |
---|---|---|---|
5 mg | Inquiry | Backorder | |
50 mg | Inquiry | Backorder |
Description | CXJ-2, a cyclic peptide, demonstrates moderate affinity for elastin-derived peptides (EDPs) and exhibits potent inhibition of the PI3K/ERK pathway, alongside significant reduction in hepatic stellate cell proliferation and migration, conferring strong antifibrotic efficacy [1]. |
In vitro | CXJ-2, at a concentration of 10 μM incubated for 24 hours, demonstrated dose-dependent inhibition of α-SMA expression in LX2 cells [1]. Additionally, CXJ-2 showed significant activity in suppressing the proliferation of LX2 cells under the same conditions [1]. |
In vivo | CXJ-2, administered intraperitoneally at a dosage of 150 μg/kg daily for three weeks, significantly alleviates liver fibrosis in mice [1]. Additionally, a single subcutaneous injection of CXJ-2 at 0.1 mg/kg exhibits favorable pharmacokinetic properties [1]. |
Molecular Weight | 1310.37 |
Formula | C55H87N15O22 |
Cas No. | 2919976-92-2 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
Copyright © 2015-2024 TargetMol Chemicals Inc. All Rights Reserved.