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Cyclo(Ile-Ala)

🥰Excellent
Catalog No. TMA1403Cas No. 90821-99-1

Helicin is a syrB inducer found in the Rosaceae family. Helicin is hydrolyzed by the enzyme BglY.

Cyclo(Ile-Ala)

Cyclo(Ile-Ala)

🥰Excellent
Purity: 99.76%
Catalog No. TMA1403Cas No. 90821-99-1
Helicin is a syrB inducer found in the Rosaceae family. Helicin is hydrolyzed by the enzyme BglY.
Pack SizePriceAvailabilityQuantity
5 mg$40In Stock
10 mg$68In Stock
25 mg$113In Stock
50 mg$166In Stock
100 mg$245In Stock
1 mL x 10 mM (in DMSO)$44In Stock
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Purity:99.76%
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Product Introduction

Bioactivity
Description
Helicin is a syrB inducer found in the Rosaceae family. Helicin is hydrolyzed by the enzyme BglY.
In vitro
To find the cell cycle inhibitors from the metabolites of Streptomyces flavoretus 18522.METHODS AND RESULTS: Activity-guided isolation was performed on the chloroform extract of the fermentation broth and mycelia of Streptomyces flavoretus 18522 by using ts FT210 cells.Compounds were isolated through various chromatoghraphic methods and elucidated by spectroscopic means.The flow cytometry was used to evaluate the cell cycle inhibiting activity of the fractions and compounds. Six cyclic dipeptides were obtained and identified as cyclo(Ala-Leu)(1),Cyclo(Ile-Ala) (2),cyclo(Ala-Val)(3),cyclo(Phe-Leu)(4),cyclo(Ala-Pro)(5) and cyclo(Phe-Val)(6).CONCLUSIONS: Compounds 1-6 are reported as new cell cycle inhibitors for the first time.
Chemical Properties
Molecular Weight184.24
FormulaC9H16N2O2
Cas No.90821-99-1
SmilesCCC(C)C1NC(=O)C(C)NC1=O
Relative Density.1.022 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 5.6 mg/mL (30.4 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM5.4277 mL27.1385 mL54.2770 mL271.3851 mL
5 mM1.0855 mL5.4277 mL10.8554 mL54.2770 mL
10 mM0.5428 mL2.7139 mL5.4277 mL27.1385 mL
20 mM0.2714 mL1.3569 mL2.7139 mL13.5693 mL

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