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D-myo-Inositol-1,4,5-triphosphate trisodium (Inositol 1,4,5-trisphosphate trisodium) is a second messenger produced in cells by the phospholipase C-mediated hydrolysis of phosphatidylinositol-4,5-bisphosphate. It binds to Ins(1,4,5)P3 receptors, resulting in the opening of calcium channels and an increase in intracellular calcium.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
500 μg | $110 | 35 days | |
5 mg | $853 | 35 days |
Description | D-myo-Inositol-1,4,5-triphosphate trisodium (Inositol 1,4,5-trisphosphate trisodium) is a second messenger produced in cells by the phospholipase C-mediated hydrolysis of phosphatidylinositol-4,5-bisphosphate. It binds to Ins(1,4,5)P3 receptors, resulting in the opening of calcium channels and an increase in intracellular calcium. |
In vitro | The dissociation constant (KD) for D-myo-Inositol-1,4,5-trisphosphate (As an inositol phosphate derivative) complexed with Pr55Gag is 2170 μM. The binding affinities of D-myo-Inositol-1,4,5-trisphosphate for matrix (MA) with KD=568 μM.[4] |
Alias | Ins(1,4,5)-P3 trisodium, Ins(1,4,5)P3, Inositol 1,4,5-trisphosphate trisodium, D-myo-Inositol-1,4,5-triphosphate (sodium salt) |
Molecular Weight | 489.06 |
Formula | C6H15Na3O15P3 |
Cas No. | 141611-10-1 |
Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
Solubility Information | PBS (pH 7.2): 50 mg/mL |
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