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Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $390 | In Stock | |
2 mg | $586 | In Stock | |
5 mg | $896 | In Stock | |
10 mg | $1,316 | In Stock | |
25 mg | $1,974 | In Stock | |
50 mg | $2,760 | In Stock |
Description | Durlobactam sodium salt (ETX2514 sodium salt) is an inhibitor of β-lactamase with IC50 values of 4 nM, 14 nM, and 190 nM for Class A KPC-2, Class C AmpC, and Class D OXA-24, respectively. Durlobactam sodium salt can be used in studies about drug-resistant Gram-negative bacteria including Acinetobacter baumannii. |
In vitro | Durlobactam sodium salt exhibited antibacterial activity against Enterobacteriaceae including E. coli, Klebsiella pneumoniae, Enterobacter cloacae, Stenotrophomonas maltophilia and Citrobacter species. Durlobactam sodium salt was also active against colistin-resistant E. coli isolates bearing the mcr-1 plasmid[1]. |
In vivo | Sulbactam–Durlobactam in thigh and lung murine infection models showed a dose-dependent reduction in MDR A. baumannii bacterial counts[1]. |
Alias | ETX2514 sodium salt |
Molecular Weight | 299.23 |
Formula | C8H10N3NaO6S |
Cas No. | 1467157-21-6 |
Storage | store at low temperature,keep away from moisture Powder: -20°C for 3 years | In solvent: -80°C for 1 year | ||||||||||||||||||||||||||||||||||||||||
Solubility Information | DMSO: 50 mg/mL (167.1 mM) ![]() H2O: 2.5 mg/mL (8.35 mM) ![]() | ||||||||||||||||||||||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||||||||||||||||||||||
DMSO/H2O
DMSO
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