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Pack Size | Price | Availability | Quantity |
---|---|---|---|
5 mg | Inquiry | Backorder | |
50 mg | Inquiry | Backorder |
Description | Endothelin-1 (1-31) (Human) TFA, a potent vasoconstrictor and hypertensive agent, originates from chymase-mediated selective hydrolysis of big ET-1 [1]. |
In vitro | Endothelin-1 (1-31) (Human) induces proliferation of human mesangial cells at concentrations of 100 pM to 100 nM over 24 hours and triggers ERK activation at 100 nM within 0 to 10 minutes [2]. |
In vivo | ET-1 (1-31) (100 nM; single dose) TFA induces constriction of mesenteric arteries in mice, likely mediated by ET A receptors, with potential age-related increases, and notable gender differences observed in chronic diabetes [1]. |
Molecular Weight | 3742.18 |
Formula | C164H237F3N38O49S5 |
Cas No. |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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