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Etaracizumab

🥰Excellent
Catalog No. T76807Cas No. 892553-42-3
Alias MEDI523, MEDI 523, LM609, LM 609, Anti-αvβ3 Integrin Recombinant Antibody

Etaracizumab (LM 609) is a humanized monoclonal antibody targeting integrin αvβ3, inhibiting angiogenesis and melanoma growth, used in the study of melanoma.

Etaracizumab

Etaracizumab

🥰Excellent
Catalog No. T76807Alias MEDI523, MEDI 523, LM609, LM 609, Anti-αvβ3 Integrin Recombinant AntibodyCas No. 892553-42-3
Etaracizumab (LM 609) is a humanized monoclonal antibody targeting integrin αvβ3, inhibiting angiogenesis and melanoma growth, used in the study of melanoma.
Pack SizePriceAvailabilityQuantity
1 mg$289In Stock
5 mg$753In Stock
10 mg$1,180In Stock
25 mg$1,780In Stock
50 mg$2,380In Stock
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Concentration:11.11 mg/mL
Purity:>95%
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Product Introduction

Bioactivity
Description
Etaracizumab (LM 609) is a humanized monoclonal antibody targeting integrin αvβ3, inhibiting angiogenesis and melanoma growth, used in the study of melanoma.
In vivo
In the SKOV3ip1 model, both Bevacizumab (5 mg/kg twice weekly) and Etaracizumab (10 mg/kg twice weekly) reduced tumor growth by 52-63%, compared with either drug alone. The combination treatment reduced growth by 63-74%.
AliasMEDI523, MEDI 523, LM609, LM 609, Anti-αvβ3 Integrin Recombinant Antibody
Chemical Properties
Molecular Weight144.3 (kDa)
Cas No.892553-42-3
Storage & Solubility Information
Storagestore at low temperature | store at -20°C | Shipping with blue ice.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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