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Fletikumab (NNC0109-0012) is a monoclonal antibody that inhibits IL-20, primarily used in research on rheumatoid arthritis and psoriasis.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $328 | In Stock | |
5 mg | $796 | In Stock | |
10 mg | $1,090 | In Stock | |
25 mg | $1,650 | In Stock | |
50 mg | $2,220 | In Stock | |
100 mg | $2,930 | In Stock |
Description | Fletikumab (NNC0109-0012) is a monoclonal antibody that inhibits IL-20, primarily used in research on rheumatoid arthritis and psoriasis. |
In vitro | Fletikumab blocks IL-20 binding to the IL-20 receptor, demonstrating a potential function in inhibiting inflammation[1]. IL-20 is a member of the IL-10 family, which includes IL-10, IL-19, IL-22, IL-24, IL-26, IL-28, and IL-29. It acts on renal cells and contributes to inflammation, fibrosis, and apoptosis through its receptors IL-20R1, IL-20R2, and IL-22R1[2]. |
Alias | NNC 0109-0012, NN-8226, Anti-IL-20 |
Molecular Weight | 146.48 kDa |
Cas No. | 1357158-22-5 |
Storage | store at low temperature | store at -80°C | Shipping with blue ice. |
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