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Fmoc-Asp-NH2
🥰Excellent
Catalog No. T17950Cas No. 200335-40-6
Fmoc-Asp-NH2 is a cleavable ADC linker utilized in the synthesis of antibody-drug conjugates (ADCs).
Fmoc-Asp-NH2
🥰Excellent
Purity: 98.41%
Catalog No. T17950Cas No. 200335-40-6
Fmoc-Asp-NH2 is a cleavable ADC linker utilized in the synthesis of antibody-drug conjugates (ADCs).
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 200 mg | $31 | In Stock | |
| 1 mL x 10 mM (in DMSO) | $29 | In Stock |
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Succinic anhydride
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Succinic anhydride is a cyclic anhydride. Succinic anhydride acts as a nonclaevable ADC linker. Succinic anhydride can react with compound 4 to link the prodrug to an amine or hydroxy 1 group of a targeting polypeptide.
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Fmoc-8-amino-3,6-dioxaoctanoic acid (Fmoc-NH-PEG2-CH2COOH) is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) and a PEG-based PROTAC linker for the synthesis of PROTACs.
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DSG Crosslinker, a cleavable ADC linker, is utilized in the synthesis of antibody-drug conjugates (ADCs).
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Fmoc-Gly-Gly-OH
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Fmoc-Gly-Gly-OH, a cleavable ADC linker, can be used in the synthesis of antibody-drug conjugates (ADCs).
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EMCS
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DSS Crosslinker
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DSS Crosslinker is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). It is a homobifunctional crosslinker that is cell membrane permeable, with amine-reactive NHS esters at both ends of an 8-atom [11.4 angstrom] spacer arm for conjugating proteins, including intracellular proteins.
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Boc-NH-PEG4-CH2COOH
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Boc-NH-PEG4-CH2COOH is a cleavable ADC linker utilized in the development of antibody-drug conjugates (ADC)[1].
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Val-cit-PAB-OH
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Val-cit-PAB-OH is an ADC linker that is cleavable.
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DSP Crosslinker
Cited
T1517557757-57-0
DSP Crosslinker, used in antibody-drug conjugates (ADCs) synthesis, is a cleavable ADC linker[1].
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CitedN-Boc-PEG5-bromide
T162181392499-32-9
N-Boc-PEG5-bromide is a cleavable ADC linker utilized in the synthesis of antibody-drug conjugates (ADCs) and serves as a PROTAC linker based on PEG and Alkyl/ether.
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Purity:98.41%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | Fmoc-Asp-NH2 is a cleavable ADC linker utilized in the synthesis of antibody-drug conjugates (ADCs). |
| In vitro | ADCs consist of an antibody attached to an ADC cytotoxin through an ADC linker. |
| Molecular Weight | 354.36 |
| Formula | C19H18N2O5 |
| Cas No. | 200335-40-6 |
| Smiles | NC(=O)[C@H](CC(O)=O)NC(=O)OCC1c2ccccc2-c2ccccc12 |
| Relative Density. | 1.362g/cm3 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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