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Fmoc-Gly-Gly-Phe-OtBu

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Catalog No. T17953Cas No. 236426-37-2

Fmoc-Gly-Gly-Phe-OtBu, a cleavable ADC linker, can be utilized in the synthesis of antibody-drug conjugates (ADCs).

Fmoc-Gly-Gly-Phe-OtBu

Fmoc-Gly-Gly-Phe-OtBu

🥰Excellent
Catalog No. T17953Cas No. 236426-37-2
Fmoc-Gly-Gly-Phe-OtBu, a cleavable ADC linker, can be utilized in the synthesis of antibody-drug conjugates (ADCs).
Pack SizePriceAvailabilityQuantity
5 mg$40In Stock
10 mg$64In Stock
25 mg$129In Stock
50 mg$198In Stock
100 mg$328In Stock
500 mg$787In Stock
1 mL x 10 mM (in DMSO)$82In Stock
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Purity:≥98%
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Product Introduction

Bioactivity
Description
Fmoc-Gly-Gly-Phe-OtBu, a cleavable ADC linker, can be utilized in the synthesis of antibody-drug conjugates (ADCs).
Chemical Properties
Molecular Weight557.64
FormulaC32H35N3O6
Cas No.236426-37-2
SmilesCC(C)(C)OC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)OCC1c2ccccc2-c2ccccc12
Relative Density.1.222 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 200 mg/mL (358.65 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.7933 mL8.9664 mL17.9327 mL89.6636 mL
5 mM0.3587 mL1.7933 mL3.5865 mL17.9327 mL
10 mM0.1793 mL0.8966 mL1.7933 mL8.9664 mL
20 mM0.0897 mL0.4483 mL0.8966 mL4.4832 mL
50 mM0.0359 mL0.1793 mL0.3587 mL1.7933 mL
100 mM0.0179 mL0.0897 mL0.1793 mL0.8966 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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