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Fucosterol

🥰Excellent
Catalog No. T8184Cas No. 17605-67-3

Fucosterol is isolated from E. stolonifera with anti-diabetic, anti-adipogenic and anti-cancer activities. It regulates adipogenesis via modulation of PPARα and C/EBPα expression.

Fucosterol

Fucosterol

🥰Excellent
Purity: 99.68%
Catalog No. T8184Cas No. 17605-67-3
Fucosterol is isolated from E. stolonifera with anti-diabetic, anti-adipogenic and anti-cancer activities. It regulates adipogenesis via modulation of PPARα and C/EBPα expression.
Pack SizePriceAvailabilityQuantity
1 mg$35In Stock
5 mg$76In Stock
10 mg$118In Stock
25 mg$238In Stock
50 mg$356In Stock
100 mg$528In Stock
500 mg$1,150In Stock
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Purity:99.68%
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Product Introduction

Bioactivity
Description
Fucosterol is isolated from E. stolonifera with anti-diabetic, anti-adipogenic and anti-cancer activities. It regulates adipogenesis via modulation of PPARα and C/EBPα expression.
In vitro
Fucosterol (0-50 μM; 7 days) suppresses the expression of PPARα and C/EBPα in fully differentiated control adipocytes [1], shows cytotoxicity against T47D and HT29 cell lines (IC50s: 27.94 and 70.41 μg/ml) [3], and decreases the proliferation of HEK293, MCF-7, and SiHa cells (IC50s: 185.4, 43.3, and 34.0 μg/ml) [4].
In vivo
Fucosterol (p.o.; 30mg/kg) causes a significant decrease in serum glucose concentrations and exhibits inhibition of sorbitol accumulations in the lenses [2].
Cell Research
Cell Line: 3T3-L1 adipocytes. Concentration: 0 μM; 25 μM; 50 μM. Incubation Time: 7 days [1]
Chemical Properties
Molecular Weight412.69
FormulaC29H48O
Cas No.17605-67-3
Smiles[H][C@@]12CC[C@H]([C@H](C)CC\C(=C\C)C(C)C)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])CC=C2CC(O)CC[C@]12C
Relative Density.0.98 g/cm3
Storage & Solubility Information
Storagestore at low temperature,keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
Ethanol: 16.67 mg/mL (4.39 mM)
Solution Preparation Table
Ethanol
1mg5mg10mg50mg
1 mM2.4231 mL12.1156 mL24.2313 mL121.1563 mL

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