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Glutaminyl Cyclase Inhibitor 1

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Catalog No. T11424Cas No. 2110449-60-8

Glutaminyl Cyclase Inhibitor 1, a glutaminyl cyclase inhibitor with an IC50 of 0.5 μM, can be utilized for studying neurological disorders.

Glutaminyl Cyclase Inhibitor 1

Glutaminyl Cyclase Inhibitor 1

🥰Excellent
Purity: 100%
Catalog No. T11424Cas No. 2110449-60-8
Glutaminyl Cyclase Inhibitor 1, a glutaminyl cyclase inhibitor with an IC50 of 0.5 μM, can be utilized for studying neurological disorders.
Pack SizePriceAvailabilityQuantity
5 mg$122In Stock
10 mg$197In Stock
25 mg$363In Stock
50 mg$592In Stock
100 mg$997In Stock
1 mL x 10 mM (in DMSO)$133In Stock
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Purity:100%
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Product Introduction

Bioactivity
Description
Glutaminyl Cyclase Inhibitor 1, a glutaminyl cyclase inhibitor with an IC50 of 0.5 μM, can be utilized for studying neurological disorders.
Targets&IC50
Glutaminyl cyclase:0.5 μM
In vitro
Glutaminyl Cyclase Inhibitor 1 is a glutaminyl cyclase inhibitor with an IC50 of 0.5 μM[1].
Chemical Properties
Molecular Weight369.43
FormulaC21H24FN3O2
Cas No.2110449-60-8
SmilesCOc1ccc(cc1OC)-c1cccc(F)c1NCCCn1cnc(C)c1
Relative Density.1.15 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
Ethanol: 80 mg/mL (216.55 mM), Sonication is recommended.
DMSO: 50 mg/mL (135.34 mM), Sonication is recommended.
Solution Preparation Table
DMSO/Ethanol
1mg5mg10mg50mg
1 mM2.7069 mL13.5344 mL27.0687 mL135.3436 mL
5 mM0.5414 mL2.7069 mL5.4137 mL27.0687 mL
10 mM0.2707 mL1.3534 mL2.7069 mL13.5344 mL
20 mM0.1353 mL0.6767 mL1.3534 mL6.7672 mL
50 mM0.0541 mL0.2707 mL0.5414 mL2.7069 mL
100 mM0.0271 mL0.1353 mL0.2707 mL1.3534 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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