GSK 3008348 hydrochloride

Name: GSK 3008348 hydrochloride
Brand: TargetMol
SKU: T15583
Price: 298 USD
Availability: InStock
Rating: 4.5 (1 reviews)

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Catalog No. T15583Cas No. 1629249-40-6

Alias GSK-3008348 hydrochloride, GSK3008348 hydrochloride

GSK 3008348 hydrochloride is an αvβ6 integrin inhibitor used to confirm idiopathic pulmonary fibrosis.

GSK 3008348 hydrochloride

😃Good

Catalog No. T15583Alias GSK-3008348 hydrochloride, GSK3008348 hydrochlorideCas No. 1629249-40-6

GSK 3008348 hydrochloride is an αvβ6 integrin inhibitor used to confirm idiopathic pulmonary fibrosis.

Pack Size	Price	Availability
1 mg	$89	Backorder
5 mg	$247	Backorder
10 mg	$347	Backorder
25 mg	$579	Backorder
50 mg	$828	Backorder
100 mg	$1,160	Backorder

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Product Introduction

Bioactivity

Description	GSK 3008348 hydrochloride is an αvβ6 integrin inhibitor used to confirm idiopathic pulmonary fibrosis.
Targets&IC50	ανβ5:6.9 (pIC50), αvβ6:8.4 (pIC50), ανβ8:7.7 (pIC50), ανβ3:6 (pIC50)
In vitro	b>METHODS: GSK 3008348 hydrochloride was subjected to fluorescence polarization assay. RESULTS: The affinity of GSK 3008348 hydrochloride for human-6 protein was 8.1 (pIC50), while its affinity in the cell adhesion assay was: 6 (pIC50) for ανβ3; 6.9 (pIC50) for ανβ5; 8.4 (pIC50) for αvβ6; and 7.7 (pIC50) for ανβ8. [1]
Alias	GSK-3008348 hydrochloride, GSK3008348 hydrochloride

Chemical Properties

Formula	C₂₉H₃₇N₅O₂ xHCl
Cas No.	1629249-40-6
Smiles	CC=1N(C2=CC([C@@H](CN3C[C@H](CCC=4NC=5C(=CC4)CCCN5)CC3)CC(O)=O)=CC=C2)N=C(C)C1.Cl xHCl
Relative Density.	no data available

Storage & Solubility Information

Storage	store at low temperature,keep away from moisture \| Powder: -20°C for 3 years \| In solvent: -80°C for 1 year \| Shipping with blue ice.
Solubility Information	DMSO: 11.66 mg/mL, Sonication and heating are recommended.

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DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

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Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

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