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GW8510 is a CDK2 (cell cycle protein-dependent kinase 2) inhibitor and RRM2 (Ribonucleotide Reductase Regulatory Subunit M2) inhibitor that affects DNA synthesis and antiproliferation in tumor cells. In mammalian aging models, GW851 improves cognition and prolongs lifespan, which may be related to the modulation of the expression of cell cycle-related protein p21 and CDK family genes, as well as the improvement of mitochondrial function.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
25 mg | $498 | In Stock | |
50 mg | $779 | In Stock | |
100 mg | $1,029 | In Stock |
Description | GW8510 is a CDK2 (cell cycle protein-dependent kinase 2) inhibitor and RRM2 (Ribonucleotide Reductase Regulatory Subunit M2) inhibitor that affects DNA synthesis and antiproliferation in tumor cells. In mammalian aging models, GW851 improves cognition and prolongs lifespan, which may be related to the modulation of the expression of cell cycle-related protein p21 and CDK family genes, as well as the improvement of mitochondrial function. |
Alias | GW-8510 |
Molecular Weight | 449.51 |
Formula | C21H15N5O3S2 |
Cas No. | 222036-17-1 |
Smiles | O=C1NC=2C=CC=3N=CSC3C2C1=CNC4=CC=C(C=C4)S(=O)(=O)NC5=NC=CC=C5 |
Relative Density. | 1.635 g/cm3 (Predicted) |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||
Solubility Information | DMSO: 20 mg/mL (44.49 mM), Sonication is recommended. | |||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||
DMSO
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