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Pack Size | Price | Availability | Quantity |
---|---|---|---|
5 mg | Inquiry | Backorder | |
50 mg | Inquiry | Backorder |
Description | HDAC8-IN-4 is a selective HDAC8 inhibitor, exhibiting inhibitory activity with IC50 values of 0.15 μM for HDAC8 and 12 μM for HDAC3 [1]. |
In vitro | HDAC8-IN-4 (Compound 9) reduces HDAC8 protein levels in HeLa cells at concentrations of 1-100 μM over a period of 5-6 days [1]. Additionally, HDAC8-IN-4 inhibits the growth of T-cell lymphoma cells (Jurkat, HH, MT4, HUT78) at approximate concentrations of 0-50 μM for 72 hours [1]. |
Molecular Weight | 342.44 |
Formula | C17H14N2O2S2 |
Cas No. | 1600528-05-9 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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