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Pack Size | Price | Availability | Quantity |
---|---|---|---|
5 mg | $446 | 6-8 weeks | |
25 mg | $1,430 | 6-8 weeks | |
50 mg | $1,860 | 6-8 weeks | |
100 mg | $2,500 | 6-8 weeks |
Description | HDACs/mTOR Inhibitor 1 is a dual HDAC and mammalian target of Rapamycin (mTOR) inhibitor for treating hematologic malignancies, with IC50 values of 0.19 nM, 1.8 nM, 1.2 nM, and >500 nM for HDAC1, HDAC6, mTOR, and PI3Kα, respectively. |
Targets&IC50 | HDAC1:0.19 nM, HDAC6:1.8 nM, mTOR:1.2 nM |
In vitro | HDACs/mTOR Inhibitor 1 stimulates cell cycle arrest in the G0/G1 phase and induces tumor cell apoptosis with low toxicity in vivo. |
Molecular Weight | 566.65 |
Formula | C28H38N8O5 |
Cas No. | 2271413-06-8 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||||||||||||||||||||||
Solubility Information | DMSO: 32.5 mg/mL (57.35 mM), Sonication is recommended. | ||||||||||||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||||||||||||
DMSO
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