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Hydroxy-PEG12-Boc (Hydroxy-PEG12-T-Butyl Ester) is a PEG-based PROTAC linker. Hydroxy-PEG12-Boc can be used in the synthesis of PROTACs.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
25 mg | $34 | In Stock | |
50 mg | $47 | In Stock |
Description | Hydroxy-PEG12-Boc (Hydroxy-PEG12-T-Butyl Ester) is a PEG-based PROTAC linker. Hydroxy-PEG12-Boc can be used in the synthesis of PROTACs. |
In vitro | PROTACs consist of two ligands connected by a linker; one ligand targets an E3 ubiquitin ligase, while the other targets the protein of interest. They utilize the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
Alias | Hydroxy-PEG12-T-Butyl Ester |
Molecular Weight | 674.82 |
Formula | C31H62O15 |
Cas No. | 2388521-20-6 |
Smiles | C(OCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCO)COCCC(OC(C)(C)C)=O |
Relative Density. | 1.092 g/cm3 (Predicted) |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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