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I2906
🥰Excellent
Catalog No. T11594Cas No. 331963-29-2
Alias I 2906
I2906 has antimicrobial activity and inhibits Mycobacterium tuberculosis.
I2906
🥰Excellent
Purity: 99.92%
Catalog No. T11594Alias I 2906Cas No. 331963-29-2
I2906 has antimicrobial activity and inhibits Mycobacterium tuberculosis.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 10 mg | $32 | In Stock | |
| 25 mg | $49 | In Stock | |
| 50 mg | $91 | In Stock | |
| 1 mL x 10 mM (in DMSO) | $119 | In Stock |
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Product Introduction
Bioactivity
Chemical Properties
| Description | I2906 has antimicrobial activity and inhibits Mycobacterium tuberculosis. |
| In vitro | I2906 exhibits excellent antimycobacterial activity and low cytotoxicity. [1] |
| In vivo | In a mouse model of Mycobacterium tuberculosis H37Rv infection, the bacterial load in the lungs and spleens of mice was significantly reduced after 4 weeks of I2906 treatment compared to untreated controls. In addition, after extending I2906 treatment to 8 weeks, the colony-forming unit counts in the lungs of mice were significantly lower than those of mice treated with isoniazid. Further studies showed that I2906 treatment significantly improved the survival rate of the mice. [1] |
| Alias | I 2906 |
| Molecular Weight | 443.58 |
| Formula | C25H37N3O4 |
| Cas No. | 331963-29-2 |
| Smiles | O=C(NNC(=O)CCCCCCCCCCCC)C=1C(=O)N(C=2C=CC=CC2C1O)CC |
| Relative Density. | 1.132 g/cm3 (Predicted) |
Storage & Solubility Information
| Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||
| Solubility Information | DMSO: 15 mg/mL (33.82 mM), Sonication is recommended. | |||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||
DMSO
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In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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