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JBSNF-000088

JBSNF-000088 is an Nicotinamide N-methyltransferase (NNMT)inhibitor. It is used for the treatment of metabolic disorders.

Catalog No. T8106Cas No. 7150-23-4

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Purity:99.89%

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COA HNMR HPLC

JBSNF-000088

Catalog No. T8106Cas No. 7150-23-4

JBSNF-000088 is an Nicotinamide N-methyltransferase (NNMT)inhibitor. It is used for the treatment of metabolic disorders.

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Pack Size	Price	Availability
200 mg	$33	In Stock
500 mg	$55	In Stock
1 g	$79	In Stock
1 mL x 10 mM (in DMSO)	$29	In Stock

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Product Introduction

Bioactivity

Description	JBSNF-000088 is an Nicotinamide N-methyltransferase (NNMT)inhibitor. It is used for the treatment of metabolic disorders.
Targets&IC50	NNMT (mouse):5.0 µM (IC50), NNMT (human):1.8 µM (IC50), NNMT (monkey):2.8 µM (IC50)
Alias	JBSNF000088

Chemical Properties

Molecular Weight	152.15
Formula	C₇H₈N₂O₂
Cas No.	7150-23-4

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

Solubility Information

DMSO: 50 mg/mL (328.62 mM)

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	6.5725 mL	32.8623 mL	65.7246 mL	328.6231 mL
5 mM	1.3145 mL	6.5725 mL	13.1449 mL	65.7246 mL
10 mM	0.6572 mL	3.2862 mL	6.5725 mL	32.8623 mL
20 mM	0.3286 mL	1.6431 mL	3.2862 mL	16.4312 mL
50 mM	0.1314 mL	0.6572 mL	1.3145 mL	6.5725 mL
100 mM	0.0657 mL	0.3286 mL	0.6572 mL	3.2862 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

Inhibitorinhibit6-MethoxynicotinamideJBSNF-000088JBSNF 000088