Shopping Cart
- Remove All
![TargetMol](https://www.targetmol.com/storage/error/oops.webp)
Your shopping cart is currently empty
Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $45 | In Stock | |
2 mg | $64 | In Stock | |
5 mg | $106 | In Stock | |
10 mg | $156 | In Stock | |
25 mg | $289 | In Stock | |
50 mg | $428 | In Stock | |
100 mg | $645 | In Stock | |
1 mL x 10 mM (in DMSO) | $122 | In Stock |
Description | KYP-2047 is a very potent, selective Prolyl oligopeptidase (POP) inhibitor. |
In vitro | In cell lines, oxidative stress induced a robust aggregation of α-synuclein,and low concentrations of KYP-2047 significantly reduced the number of cells with α-synuclein inclusions while abolishing the colocalization of α-synuclein and PREP. KYP-2047 significantly reduced the amount of aggregated α-synuclein,and it had beneficial effects on cell viability.?In the transgenic mice, a 5-day treatment with the PREP inhibitor reduced the amount of α-synuclein immunoreactivity and soluble α-synuclein protein in the brain[1]. |
Molecular Weight | 339.43 |
Formula | C20H25N3O2 |
Cas No. | 796874-99-2 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | ||||||||||||||||||||||||||||||
Solubility Information | DMSO: 25 mg/mL (73.65 mM) ![]() | ||||||||||||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||||||||||||
DMSO
|
Copyright © 2015-2024 TargetMol Chemicals Inc. All Rights Reserved.