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POP-IN-2 (Compound 7k) is a potent, covalently bound inhibitor of prolyl oligopeptidase (POP) (Ki: 6 nM).POP-IN-2 can be used in neurodegenerative disease and cancer research.

POP-IN-1 (Compound 12h) is an effective POP inhibitor (Ki=0.009 μM）. POP-IN-1 has research potential in neurodegenerative diseases and cancer progression

Lipopolysaccharides (LPS) is a unique component of the cell wall of Gram-negative bacteria and consists of three regions: lipid A, oligosaccharide core, and O-specific polysaccharide (O-antigen). Lipopolysaccharides help maintain the integrity of the outer cell membrane and protect bacteria from damage by bile salts and lipid antibiotics. Lipopolysaccharides is a highly immunogenic antigen that can enhance immune responses and can be used for inflammation model construction.

SPOP-IN-6b is an effective inhibitor of speckle-type POZ protein (SPOP) with an IC50 of 3.58 μM and can be used in stuides about the treatment of renal cancer.

SPOP-IN-6lc is a potent SPOP inhibitor with multiple roles in cancer, oncostatic in a variety of tumors, but functions as an oncogene in renal cancer.SPOP-IN-6lc can be used to study cell signaling and apoptosis.

POPG is a useful organic compound for research related to life sciences. The catalog number is TF0085 and the CAS number is 268550-95-4.

POPS is a useful organic compound for research related to life sciences. The catalog number is TF0061 and the CAS number is 321863-21-2.

Rezatapopt is an antineoplastic agent designed to inhibit solid tumors harboring p53 mutations [1].

Isoapoptolidin is a stable derivative of apoptolidin that demonstrates 10-fold reduced F1FO-ATP synthase inhibitory activity compared to apoptolidin (IC50s = 17 and 0.7 μM, respectively).

(Rac)-POPC serves as a model phosphatidylcholine utilized in the preparation of giant vesicles (GVs) [1].

Prostate apoptosis response protein PAR-4 (2-7) [Homo sapiens] is a peptide with the sequence H2N-Ala-Thr-Gly-Gly-Tyr-Arg-OH, MW= 623.66.

Populin is a useful organic compound for research related to life sciences. The catalog number is T123815 and the CAS number is 99-17-2.

Epoprostenol, a prostaglandin, is a powerful vasodilator. It inhibits platelet aggregation.

Apoptosis Inducer 12 (Compound 3z) is a compound that promotes cell death via the mitochondrial pathway and is utilized in cancer research [1].

Apoptolidin is an apoptosis inducer originally isolated from Nocardiopsis bacteria. It inhibits the mitochondrial F1FO ATPase (Ki = 4-5 μM). Apoptolidin selectively kills transformed glial cells without significantly affecting untransformed cells. It also has antibiotic and antifungal actions.

RGD-Targeted Proapoptotic Peptide is a peptide that preferentially binds to integrins at sites of tumor angiogenesis through its C-terminal RGD-4C sequence (ACDCRGDCFC).

Epoprostenol sodium is a potent inhibitor of platelet aggregation used in pulmonary hypertension and transplantation.

Hypophyllanthin and phyllanthin have antitumour effects against Ehrlich Ascites Carcinoma in mice.

Populoside is a useful organic compound for research related to life sciences. The catalog number is T125159 and the CAS number is 26632-35-9.

2-Bromobiphenyl is a persistent organic pollutant (POP) found primarily in soil and water. It is a known human carcinogen and has been linked to a variety of health effects including reproductive and developmental toxicity.

CoPoP, a liposome-based vaccine adjuvant, holds potential for application in cancer research [1].

Apoptosis Inducer 5, a lignan enantiomer extracted from Crataegus pinnatifida, demonstrates cytotoxic properties through inducing apoptosis and autophagy in Hep3B cells.

Apoptosis Inducer 3 (Compound 3), a selective apoptosis triggering agent, induces both apoptosis and late-apoptosis phases, demonstrating cytotoxic effects against cancer cells [1].

The compound, tumor-targeted pro-apoptotic peptide (CNGRC-GG-D(KLAKLAK)2), functions as an anti-tumor agent by disrupting mitochondrial membranes to induce apoptosis, demonstrating anticancer efficacy in mice [1].

Eprenetapopt (PRIMA-1Met) restores wild-type conformation and function to mutant p53, and triggers apoptosis in tumor cells. PRIMA-1MET also targets the selenoprotein thioredoxin reductase 1 (TrxR1), a key regulator of cellular redox balance.

Lipopeptin A is a lipoprotein subclass that is a risk factor for atherosclerotic diseases such as coronary heart disease and stroke.

SPOP-IN-6b dihydrochloride is a potent inhibitor of spotted POZ protein (SPOP) (IC50: 3.58 μM).

Apoptotic agent-2 is capable of downregulating Bcl-2 and upregulating Bax and caspase-3 to induce apoptosis, exhibiting anti-proliferative effects that can be used in cancer research.

POPSO is a useful organic compound for research related to life sciences and the catalog number is T65399.

Apoptosis Inducer 4 (Compound 12b) is a compound that induces apoptosis and exhibits anticancer properties [1].

TPOP146 is a selective CBP/P300 benzoxazepine bromodomain inhibitor (Kd: 134 nM and 5.02 μM for CBP and BRD4).

Poppy acid is a useful organic compound for research related to life sciences and the catalog number is T131392.

Apoptozole (Apoptosis Activator VII) is an inhibitor of the ATPase domain of Hsc70 and Hsp70, and can induce apoptosis.

POPE is a compound found in Escherichia coli, part of the cell membrane, and can be used to study changes in cell membrane permeability.

Apoptotic agent-1 (Compound 8a) induces Fas receptor and Cyto C genes over-expression that is an apoptotic agent with high antiproliferative activity against cancer cells as well as low cytotoxic effect [1].

β-Apopicropodophyllin, a natural product isolated from Hyptis wticillata, promotes apoptosis through mechanisms including microtubule disruption, DNA damage, cell cycle arrest, and ER stress. This compound holds potential for cancer research applications [1].

Apoptosis inducer 5D is a new type of inducer that induces cell death by activating the apoptosis of cancer cells.

SPOP-IN-6b hydrochloride is a highly effective inhibitor of speckle-type POZ protein (SPOP), exhibiting an IC50 value of 3.58 μM.

Apoptosis Inducer 13 (Compound Ru4) promotes apoptosis in cancer cells while also suppressing their migration and invasion. Additionally, it facilitates the conversion of coenzyme NADH to NAD+, and elevates intracellular ROS levels [1].

Apoptotic agent-3 utilizes a potential mitochondrial-mediated Bcl-2/Bax pathway and activates the caspase-3 pathway to promote apoptosis, exhibiting anti-proliferative effects that can be used to study cancer.

Lipopolysaccharides, Escherichiacoli (E. coli O111:B4) is a unique component of the cell wall of Gram-negative bacteria, consisting of three regions: lipid A, oligosaccharide core and O-specific polysaccharide (O-antigen). Lipopolysaccharides, Escherichiacoli helps maintain the integrity of the outer cell membrane and protects bacteria from damage by bile salts and lipid antibiotics. Lipopolysaccharides, Escherichiacoli is a highly immunogenic antigen that can enhance immune responses and can be used for inflammation model construction.

Apoptosis inducer 6 is an anticancer agent with broad-spectrum anticancer activity that induces apoptosis, which triggers cell death.

Apoptosis inducer 8 is a galectin-1 (gal-1)-mediated apoptosis inducer and a PET imaging agent that significantly reduces gal-1 protein levels and can be used in major lung cancer studies worldwide.

Apoptosis Inducer 11 (compound 3u) promotes apoptosis via the mitochondrial pathway and elicits a G2/M block alongside a marked reduction in the S phase within non-Hodgkin lymphoma cell lines [1].

Apoptosis inducer 10 is a potent apoptosis inducer with anti-proliferative activity. apoptosis inducer 10 induces apoptosis in HeLa cancer cells using a mitochondria-dependent endogenous pathway.

Lipoprotein lipase, a multifunctional enzyme present in adipose tissue, heart, skeletal muscle, islets, and macrophages, plays a crucial role in normal lipoprotein metabolism, and the distribution and utilization of tissue-specific substrates. This enzyme catalyzes the rate-limiting step of lipids within the blood circulation [1] [2].

Linderene acetate is a competitive inhibitor against Prolyl endopeptidase.

Leojaponin is a prolyl oligopeptidase (POP) inhibitor. Leojaponin exhibits significant cytoprotective activities against glutamate-induced toxicity at concentrations ranging from 0.1 microm to 10 microm.

BR102910 (4-Thiazolecarboxamide, N-[2-[(2S)-2-cyano-4,4-difluoro-1-pyrrolidinyl]-2-oxoethyl]-2-[(3,4-dichlorophenyl)methyl]-) is a selective inhibitor of fibroblast activated protein (FAP).

β-Elemonic Acid (3-Oxotirucallenoic Acid) exhibits anti-inflammatory effects. Beta-Elemonic acid inhibits proliferation by inducing hypoploid cells and cell apoptosis, the anticancer effects of beta-Elemonic acid are related to the MAPK signaling pathway, ROS activation and glutathione depletion in human A549 lung cancer cells. Beta-Elemonic acid exhibits prolyl endopeptidase inhibitory activities.