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Liothyronine sodium hydrate
🥰Excellent
Catalog No. T64268Cas No. 345957-19-9
Alias Triiodothyronine sodium hydrate, T3 sodium hydrate, 3,3',5-Triiodo-L-thyronine sodium hydrate
Liothyronine sodium hydrate (Triiodothyronine sodium hydrate) is a TRα and TRβ agonist and a thyroxine analog with anticancer and antitumor activities. It can be used to study hypothyroidism, stroke and cognitive dysfunction.
Liothyronine sodium hydrate
🥰Excellent
Catalog No. T64268Alias Triiodothyronine sodium hydrate, T3 sodium hydrate, 3,3',5-Triiodo-L-thyronine sodium hydrateCas No. 345957-19-9
Liothyronine sodium hydrate (Triiodothyronine sodium hydrate) is a TRα and TRβ agonist and a thyroxine analog with anticancer and antitumor activities. It can be used to study hypothyroidism, stroke and cognitive dysfunction.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 10 mg | $36 | In Stock | |
| 25 mg | $54 | In Stock | |
| 50 mg | $77 | In Stock | |
| 100 mg | $110 | In Stock |
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Triostat, T3 Sodium salt, Sodium L-3,3',5-triiodothyronine, Cytomel, 3,3',5-Triiodo-L-thyronine sodium
T166955-06-1
Liothyronine Sodium is the sodium salt form of liothyronine, a synthetic form of the levorotatory isomer of the naturally occurring thyroid hormone triiodothyronine (T3). Liothyronine sodium (3,3',5-Triiodo-L-thyronine sodium) binds to nuclear thyroid receptors which then bind to thyroid hormone response elements of target genes. As a result, liothyronine sodium induces gene expression that is required for normal growth and development. Liothyronine sodium is more potent and has a more rapid action than thyroxine (T4).
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PCO371
2,4-Imidazolidinedione, 1-(3,5-dimethyl-4-(2-((4-oxo-2-(4-(trifluoromethoxy)phenyl)-1,3,8-triazaspiro(4.5)dec-1-en-8-yl)sulfonyl)ethyl)phenyl)-5,5-dimethyl-
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | Liothyronine sodium hydrate (Triiodothyronine sodium hydrate) is a TRα and TRβ agonist and a thyroxine analog with anticancer and antitumor activities. It can be used to study hypothyroidism, stroke and cognitive dysfunction. |
| Targets&IC50 | TRα (human):2.33 nM, TRβ (human):2.33 nM |
| In vitro | b>METHODS: Liothyronine sodium hydrate (100 μM, 3 weeks) was used to treat liver cancer cells (Mahlavu, SK-Hep-1, J5, 5328 and HepG2) and the cell growth was observed. RESULTS: Liothyronine sodium hydrate can stimulate the proliferation of liver cancer cells. [1] |
| Alias | Triiodothyronine sodium hydrate, T3 sodium hydrate, 3,3',5-Triiodo-L-thyronine sodium hydrate |
| Formula | C15H11NNaO4 xH2O |
| Cas No. | 345957-19-9 |
| Smiles | IC(C=C(C=C1I)C[C@H](N)C([O-])=O)=C1OC2=CC(I)=C(C=C2)O.[Na+].O xH2O |
Storage & Solubility Information
| Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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