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Liothyronine sodium
Liothyronine Sodium is the sodium salt form of liothyronine, a synthetic form of the levorotatory isomer of the naturally occurring thyroid hormone triiodothyronine (T3). Liothyronine sodium (3,3',5-Triiodo-L-thyronine sodium) binds to nuclear thyroid receptors which then bind to thyroid hormone response elements of target genes. As a result, liothyronine sodium induces gene expression that is required for normal growth and development. Liothyronine sodium is more potent and has a more rapid action than thyroxine (T4).
Catalog No. T1669Cas No. 55-06-1
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Liothyronine sodium
Catalog No. T1669Alias Triostat, T3 Sodium salt, Sodium L-3,3',5-triiodothyronine, Cytomel, 3,3',5-Triiodo-L-thyronine sodiumCas No. 55-06-1
Liothyronine Sodium is the sodium salt form of liothyronine, a synthetic form of the levorotatory isomer of the naturally occurring thyroid hormone triiodothyronine (T3). Liothyronine sodium (3,3',5-Triiodo-L-thyronine sodium) binds to nuclear thyroid receptors which then bind to thyroid hormone response elements of target genes. As a result, liothyronine sodium induces gene expression that is required for normal growth and development. Liothyronine sodium is more potent and has a more rapid action than thyroxine (T4).
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose. | Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 mg | $47 | In Stock | |
| 200 mg | $68 | In Stock | |
| 500 mg | $117 | In Stock | |
| 1 mL x 10 mM (in DMSO) | $30 | In Stock |
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Liothyronine
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Triiodothyronine, Tresitope, O-(4-Hydroxy-3-iodophenyl)-3,5-diiodo-L-tyrosine, Lyothyronine, L-3,3',5-Triiodothyronine, 3,3',5-Triiodo-L-thyronine
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Liothyronine (Tresitope) is an active form of thyroid hormone, binding to β1 thyroid hormone receptor (TRβ1), and activates its activity.
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CitedLiothyronine Cited
Triiodothyronine, Tresitope, O-(4-Hydroxy-3-iodophenyl)-3,5-diiodo-L-tyrosine, Lyothyronine, L-3,3',5-Triiodothyronine, 3,3',5-Triiodo-L-thyronine
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Liothyronine (Tresitope) is an active form of thyroid hormone, binding to β1 thyroid hormone receptor (TRβ1), and activates its activity.
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CitedLiothyronine Cited
Triiodothyronine, Tresitope, O-(4-Hydroxy-3-iodophenyl)-3,5-diiodo-L-tyrosine, Lyothyronine, L-3,3',5-Triiodothyronine, 3,3',5-Triiodo-L-thyronine
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Liothyronine (Tresitope) is an active form of thyroid hormone, binding to β1 thyroid hormone receptor (TRβ1), and activates its activity.
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L-Thyroxine
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L-Thyroxine (NSC 36397) is the major hormone derived from the thyroid gland. L-Thyroxine (NSC 36397) is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. L-Thyroxine (NSC 36397) is released from thyroglobulin by proteolysis and secreted into the blood. L-Thyroxine (NSC 36397) is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism.
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Product Introduction
Bioactivity
Chemical Properties
| Description | Liothyronine Sodium is the sodium salt form of liothyronine, a synthetic form of the levorotatory isomer of the naturally occurring thyroid hormone triiodothyronine (T3). Liothyronine sodium (3,3',5-Triiodo-L-thyronine sodium) binds to nuclear thyroid receptors which then bind to thyroid hormone response elements of target genes. As a result, liothyronine sodium induces gene expression that is required for normal growth and development. Liothyronine sodium is more potent and has a more rapid action than thyroxine (T4). |
| In vivo | The chemical properties of Liothyronine Sodium are nearly identical to those of Triiodothyronine, acting on thyroid hormone receptors alpha and beta-1. As the most potent form of thyroid hormone, Liothyronine Sodium can increase the basal metabolic rate, affect protein synthesis, and enhance the body's sensitivity to catecholamines (such as adrenaline). |
| Alias | Triostat, T3 Sodium salt, Sodium L-3,3',5-triiodothyronine, Cytomel, 3,3',5-Triiodo-L-thyronine sodium |
| Molecular Weight | 672.96 |
| Formula | C15H11I3NNaO4 |
| Cas No. | 55-06-1 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||
| Solubility Information | DMSO: 15 mg/mL (22.29 mM), Sonication is recommended.  | |||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||
DMSO
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
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