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L-Thyroxine sodium (LT4 sodium), the major hormone derived from the thyroid gland, is the agonist of Thyroid hormone receptor alpha and beta.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
500 mg | $47 | In Stock | |
1 g | $62 | In Stock | |
1 mL x 10 mM (in DMSO) | $52 | In Stock |
Description | L-Thyroxine sodium (LT4 sodium), the major hormone derived from the thyroid gland, is the agonist of Thyroid hormone receptor alpha and beta. |
In vitro | evothyroxine (L-T(4))can upregulate the expression of P-gp mRNA and protein in LS180 cells, but only L-T(4) and L-T(3) can produce the same effect in Caco-2 cells, which are relatively lacking in PXR[1] |
Cell Research | Cell lines: LS180V cells. Concentrations: 100 nM and 100μM. Incubation Time: 72 h. Method: LS180V cells are induced for 72 h with two l-T4 concentrations of 100 nM and 100 μM. |
Animal Research | Animal Models: SD rats. Dosages: 20 μg/kg/day and 100 μg/kg/day. Administration: i.p. |
Alias | L-T4 sodium, LT4 sodium, Levothyroxine sodium |
Molecular Weight | 798.85 |
Formula | C15H10I4NO4.Na |
Cas No. | 55-03-8 |
Smiles | [Na+].N[C@@H](Cc1cc(I)c(Oc2cc(I)c(O)c(I)c2)c(I)c1)C([O-])=O |
Relative Density. | no data available |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||
Solubility Information | DMSO: 27.5 mg/mL (34.38 mM) | |||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||
DMSO
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