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L-Thyroxine sodium

L-Thyroxine sodium
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Purity:99.56%
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L-Thyroxine sodium

Catalog No. T22355Cas No. 55-03-8
L-Thyroxine sodium (LT4 sodium), the major hormone derived from the thyroid gland, is the agonist of Thyroid hormone receptor alpha and beta.
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Pack SizePriceAvailabilityQuantity
500 mg$47In Stock
1 g$62In Stock
1 mL x 10 mM (in DMSO)$52In Stock
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Product Introduction

Bioactivity
Description
L-Thyroxine sodium (LT4 sodium), the major hormone derived from the thyroid gland, is the agonist of Thyroid hormone receptor alpha and beta.
In vitro
evothyroxine (L-T(4))can upregulate the expression of P-gp mRNA and protein in LS180 cells, but only L-T(4) and L-T(3) can produce the same effect in Caco-2 cells, which are relatively lacking in PXR[1]
Cell Research
Cell lines: LS180V cells. Concentrations: 100 nM and 100μM. Incubation Time: 72 h. Method: LS180V cells are induced for 72 h with two l-T4 concentrations of 100 nM and 100 μM.
Animal Research
Animal Models: SD rats. Dosages: 20 μg/kg/day and 100 μg/kg/day. Administration: i.p.
AliasLT4 sodium, Levothyroxine sodium, L-T4 sodium
Chemical Properties
Molecular Weight798.85
FormulaC15H10I4NO4.Na
Cas No.55-03-8
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year
Solubility Information
DMSO: 27.5 mg/mL (34.38 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.2518 mL6.2590 mL12.5180 mL62.5900 mL
5 mM0.2504 mL1.2518 mL2.5036 mL12.5180 mL
10 mM0.1252 mL0.6259 mL1.2518 mL6.2590 mL
20 mM0.0626 mL0.3129 mL0.6259 mL3.1295 mL

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