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Lobetyolinin

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Catalog No. TN1876Cas No. 142451-48-7

Lobetyolinin is a compound from Codonopsis pilosula with acetylcholinesterase (AChE) inhibitory and antiarrhythmic activities.

Lobetyolinin

Lobetyolinin

🥰Excellent
Catalog No. TN1876Cas No. 142451-48-7
Lobetyolinin is a compound from Codonopsis pilosula with acetylcholinesterase (AChE) inhibitory and antiarrhythmic activities.
Pack SizePriceAvailabilityQuantity
1 mg$106In Stock
5 mg$328In Stock
10 mg$492In Stock
25 mg$787In Stock
50 mg$1,070In Stock
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Product Introduction

Bioactivity
Description
Lobetyolinin is a compound from Codonopsis pilosula with acetylcholinesterase (AChE) inhibitory and antiarrhythmic activities.
In vivo
METHODS: Lobetyolinin (50 μM, 24 hours) was used to treat zebrafish larvae with 15 μM terfenadine for 2 hours, and the heartbeat was recorded under fluorescence.
RESULTS:As a result, the heart rate of zebrafish larvae recovered to varying degrees, and Lobetyolinin showed better activity. [1]
METHODS: After 1 hour of treatment with 25 μM terfenadine, the heart rate decreased and irregular rhythm appeared. After 6 hours of pretreatment with Lobetyolinin, the electrocardiogram of adult zebrafish treated with it was measured.
RESULTS:Lobetyolinin restored the heart rate of adult zebrafish, indicating that it has anti-arrhythmic effects. [1]
Chemical Properties
Molecular Weight558.57
FormulaC26H38O13
Cas No.142451-48-7
SmilesO([C@@H]([C@@H](C#CC#C/C=C/C)O)/C=C/CCCO)[C@@H]1O[C@H](CO[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)[C@@H](O)[C@H](O)[C@H]1O
Relative Density.1.48g/cm3
Storage & Solubility Information
Storagestore at low temperature,keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
Ethanol: 80 mg/mL (8.95 mM), Sonication is recommended.
Solution Preparation Table
Ethanol
1mg5mg10mg50mg
1 mM1.7903 mL8.9514 mL17.9029 mL89.5143 mL
5 mM0.3581 mL1.7903 mL3.5806 mL17.9029 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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